Q8EB01

PR
Gene name
cysH
Protein name
Phosphoadenosine 5'-phosphosulfate reductase
Names
PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase
Species
Shewanella oneidensis (strain MR-1)
KEGG Pathway
son:SO_3736
EC number
1.8.4.8: With a disulfide as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8EB01

Entry ID Method Resolution Chain Position Source
AF-Q8EB01-F1 Predicted AlphaFoldDB

No variants for Q8EB01

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EB01

No associated diseases with Q8EB01

1 regional properties for Q8EB01

Type Name Position InterPro Accession
domain Phosphoadenosine phosphosulphate reductase 47 - 219 IPR002500

Functions

Description
EC Number 1.8.4.8 With a disulfide as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
phosphoadenylyl-sulfate reductase (thioredoxin) activity Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.

2 GO annotations of biological process

Name Definition
hydrogen sulfide biosynthetic process The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSSELKALL TAPKSVQQAE LERINRFLAG LTAQERVLWG LAYLPGNHAL SSSFGIQAAV
70 80 90 100 110 120
MLHMVSQVQS DIPVILTDTG YLFPETYQFI DQLTERLSLN LKVYQAPITS AWQEARFGQL
130 140 150 160 170 180
WEQGVEGLER YNRLNKVEPM QRALAELEVG TWFAGLRRSQ SSTREELPIL AIHGSRFKLL
190 200 210 220 230 240
PIIEWSNKDV HLYLTQFDLP YHPLWEQGYV SVGDTHSSKP LELGMTEEET RFNGLKRECG
LHYEI