Q8E1B0
Gene name |
asnA |
Protein name |
Aspartate--ammonia ligase |
Names |
Asparagine synthetase A |
Species |
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) |
KEGG Pathway |
sag:SAG0450 |
EC number |
6.3.1.1: Acid--ammonia (or amine) ligases (amide synthases) |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8E1B0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8E1B0-F1 | Predicted | AlphaFoldDB |
No variants for Q8E1B0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8E1B0 | |||||
No associated diseases with Q8E1B0
1 regional properties for Q8E1B0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | NADPH-dependent FMN reductase-like | 36 - 179 | IPR005025 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.1.1 | Acid--ammonia (or amine) ligases (amide synthases) |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| aspartate-ammonia ligase activity | Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| L-asparagine biosynthetic process | The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKKSFIHQQQ | EISFVKNTFT | QYLIDKLEIV | EVQGPILSQV | GDGMQDNLSG | IEHPVSVKVL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NIPEAEFEVV | HSLAKWKRHT | LARFGFNEGE | GLFVHMKALR | PDEDSLDPTH | SVYVDQWDWE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KVIPDGRRNL | DYLKETVEKI | YKAIRLTELA | VEARFDIESI | LPKRITFIHT | EELVEKYPDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SPKERENAIA | KEYGAVFLIG | IGGELADGKP | HDGRAPDYDD | WTTPSENGFK | GLNGDILVWN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EQLGTAFELS | SMGIRVDEDA | LKRQVVLTGD | EDRLEFEWHK | TLLRGFFPLT | IGGGIGQSRL |
| 310 | 320 | ||||
| AMFLLRKKHI | GEVQSSVWPK | EVRDTFENIL |