Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8DI83

Entry ID Method Resolution Chain Position Source
AF-Q8DI83-F1 Predicted AlphaFoldDB

No variants for Q8DI83

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8DI83

No associated diseases with Q8DI83

3 regional properties for Q8DI83

Type Name Position InterPro Accession
conserved_site Chaperonin TCP-1, conserved site 37 - 49 IPR002194-1
conserved_site Chaperonin TCP-1, conserved site 58 - 74 IPR002194-2
conserved_site Chaperonin TCP-1, conserved site 86 - 94 IPR002194-3

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
metal ion binding Binding to a metal ion.
metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

2 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMSYSLRVAD LPAGDRPREK LLSQGARYLS SAELLAILLG TGQGAGKLSA VGLGQFILKQ
70 80 90 100 110 120
LGERTGDSTD AVSALRDITP EELMAIPGVG PAKATTILAA VELGKRVFQS RPGEQTIIDS
130 140 150 160 170 180
PALAAAVLAA DLMWQATERF AVLLLDVRHR LLGSHVITVG TATETLAHPR EIFREAVRRN
190 200 210 220 230 240
ASRLIIAHNH PSGNLSPSQA DLDLTKQILQ AGQLMEIPVL DHLILGNGDY QSLREITPLW
QQVPQGDGSA