Q8DG71

PR
Gene name
clpB2 (tll2453)
Protein name
Chaperone protein ClpB 2
Names
Species
Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)
KEGG Pathway
tel:tll2453
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

114-186 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8DG71

Entry ID Method Resolution Chain Position Source
AF-Q8DG71-F1 Predicted AlphaFoldDB

No variants for Q8DG71

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8DG71

No associated diseases with Q8DG71

9 regional properties for Q8DG71

Type Name Position InterPro Accession
domain AAA+ ATPase domain 199 - 344 IPR003593-1
domain AAA+ ATPase domain 611 - 757 IPR003593-2
domain ATPase, AAA-type, core 204 - 336 IPR003959-1
domain ATPase, AAA-type, core 610 - 774 IPR003959-2
domain Clp, repeat (R) domain 6 - 147 IPR004176
conserved_site ClpA/B, conserved site 1 296 - 308 IPR018368
domain Clp ATPase, C-terminal 781 - 870 IPR019489
conserved_site ClpA/B, conserved site 2 645 - 663 IPR028299
domain ClpA/ClpB, AAA lid domain 344 - 436 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQPTDPTKFT DKAWEAIVKS QDVAREYRSQ YLETEHVMIA LLREEGLGQV ILERSDIDTE
70 80 90 100 110 120
WVLKRLMDFA RQQPRVPAGS ELYCGRSLDA LLDEANRLRQ EEEDQFISIE HLLLAFVGDR
130 140 150 160 170 180
RIGQRLFRAL NCDRQQLAAT VKAIRGAQKV LDQNPENKYA ALEKYGRDLT EAARQGKLDP
190 200 210 220 230 240
VIGRDEEIRR VIQVLSRRTK NNPVLIGEPG VGKTAIAEGL AQRIINGDVP ESLKNRRLIS
250 260 270 280 290 300
LDLGSLVAGA KFRGDFEDRL KAVLHEVTHS EGQIVLFIDE LHTVVGAGAN QNSSMDASNL
310 320 330 340 350 360
LKPMLARGEL RCIGATTLDE YRKYIEKDAA LERRFQQVYI GQPSVEDTIS ILRGLKDRYE
370 380 390 400 410 420
IHHNVKITDS ALVAAAMLSD RYISDRYLPD KAIDLVDEAA AKLKMEITTK PAELEALERR
430 440 450 460 470 480
LRQLEMERLS LKQEESLPLS QAPLQATRDR LQRIEAEIAQ LQPRQQAMQA RWQAEKELLE
490 500 510 520 530 540
RINSLKEEED QVKLQIEQAE RDYNLNKAAQ LKYGRLETLQ RELEATEAQL LELQAAGGTF
550 560 570 580 590 600
LRDQVTEADI AEIVAKWTGI PLQKLMASER QKLLQLEQVL HQRVIGQSDA VAAVAAAIRR
610 620 630 640 650 660
ARAGMKDPAR PIGSFLFMGP TGVGKTELAR ALAEALFDDE NALVRIDMSE YMEKHAVSRM
670 680 690 700 710 720
IGAPPGYVGF DSGGQLTEAI RRRPYAVVLF DEVEKAHPEV FNVLLQVLDD GRITDSQGRT
730 740 750 760 770 780
VDFRNTVIIM TSNLGSEHIL DLAADDSRYE EMRQRVLQSA QKYFRPEFLN RIDDVILFHG
790 800 810 820 830 840
LGRTELAQIA QIQLRRVEKL LADQKIHLRL TPAALDHLVA VGFDPVYGAR PLKRAIQREL
850 860 870 880
ENPLAVKLLE EVFTPGDTIL VDLVGSELTF RAVSPAGTGD RDTVSAS