Q8DC60
Gene name |
ispD |
Protein name |
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase |
Names |
4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT |
Species |
Vibrio vulnificus (strain CMCP6) |
KEGG Pathway |
vvu:VV1_1582 |
EC number |
2.7.7.60: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8DC60
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8DC60-F1 | Predicted | AlphaFoldDB |
No variants for Q8DC60
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8DC60 | |||||
No associated diseases with Q8DC60
1 regional properties for Q8DC60
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site | 106 - 113 | IPR018294 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.60 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity | Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway | The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate. |
| terpenoid biosynthetic process | The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARSMTSLVA | VVPAAGVGSR | MKADRPKQYL | QIHGKTILEH | TIERLLSHPA | ITQVVVAVSE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DDPYYSELAI | AQHPDIVRVA | GGKERADSVL | SALRFLSLQQ | QKADWVLVHD | AARPCVAHQD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IDALIERCSS | HETGGILATP | VRDTMKRANA | QQMIDHTVDR | NALWHALTPQ | MFKAEVLTDA |
| 190 | 200 | 210 | 220 | 230 | |
| LSDALAQGVA | ITDEASALEW | RGELPALVQG | CSSNIKVTQP | EDLALAEFYL | SREKDRK |