Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8D8M2

Entry ID Method Resolution Chain Position Source
AF-Q8D8M2-F1 Predicted AlphaFoldDB

No variants for Q8D8M2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8D8M2

No associated diseases with Q8D8M2

4 regional properties for Q8D8M2

Type Name Position InterPro Accession
domain FtsK domain 600 - 839 IPR002543
domain FtsK gamma domain 917 - 982 IPR018541
domain DNA translocase FtsK, 4TM region 29 - 199 IPR025199
domain FtsK alpha domain 492 - 592 IPR041027

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
  • Located at the septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFKENAKKVQ TIIKTSEEAQ SSRLNGFQRL KECCLILGVL TSAFLSIALL TFSPADPSWS
70 80 90 100 110 120
QTSWGGDISN AGGQFGAWVA DTLFFTFGLL AYLLPVLLVI VTWVFFRTRD EDEHIDLMLW
130 140 150 160 170 180
GTRLLGLAIL ILTSCGLADI NFDDIWYFSS GGVLGDVLNS LALPTLNLLG TTLVLLFAWG
190 200 210 220 230 240
AGFTLLTGIS WLSIVEWIGS LFLDVCQWAL NRLRGEKTEV IAPELQPIAL SDDEPKAQPQ
250 260 270 280 290 300
IEAQQDEIVE EERIPDPLPV EPVVQMRREY PIHMPQTVSY QTVSDELDEL EDNSFERAKK
310 320 330 340 350 360
LNATIEELEQ EALSVNDLPD DTMSTERARY NVADIAQVSA EHSQTTQVEH AQDFSVDVEE
370 380 390 400 410 420
FDHVISLSEL DKISEEIDEP VMVGFAEEAP LHHNEAQRSA MASSAEPMFS HLGVEQTTQH
430 440 450 460 470 480
TTQEEIVDLP VADSVGDVNP EMEDYVEEDE DQDQDVVAFQ NMVSKAQQNM AATQNPFLMK
490 500 510 520 530 540
QDTSLPVPKE PLPTLELLYH PEKRENFIDK EALEQVARLV ESKLADYKIT AEVVGIFPGP
550 560 570 580 590 600
VITRFELDLA PGVKVSRISS LSMDLARSLS AMAVRVVEVI PGKPYVGLEL PNMSRQTVYL
610 620 630 640 650 660
SDVIDSPQFQ NATSPTTVVL GQDIAGEALV ADLAKMPHVL VAGTTGSGKS VGVNVMILSM
670 680 690 700 710 720
LYKASPEDVR FIMIDPKMLE LSVYEGIPHL LAEVVTDMKD ASNALRWCVG EMERRYKLMS
730 740 750 760 770 780
VMGVRNIKGF NEKLKMAADA GHPIHDPFWQ EGDSMDTEPP LLEKLPYIVV VVDEFADLMM
790 800 810 820 830 840
VVGKKVEELI ARLAQKARAA GIHLILATQR PSVDVITGLI KANIPTRVAF TVSTKTDSRT
850 860 870 880 890 900
ILDQGGAESL LGMGDMLYLP PGSSHTIRVH GAFASDDDVH AVVNNWKARG KPNYIDEIIS
910 920 930 940 950 960
GEQGPESLLP GEQMESDEDL DPLFDQVVEH VVQSRRGSVS GVQRRFKIGY NRAARIVEQL
970 980
EAQGIVSAPG HNGNREVLAP APPRE