Q8CWY6

PR
Gene name
glyQ
Protein name
Glycine--tRNA ligase alpha subunit
Names
Glycyl-tRNA synthetase alpha subunit, GlyRS
Species
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
KEGG Pathway
smu:SMU_445
EC number
6.1.1.14: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

31-115 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8CWY6

Entry ID Method Resolution Chain Position Source
AF-Q8CWY6-F1 Predicted AlphaFoldDB

No variants for Q8CWY6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8CWY6

No associated diseases with Q8CWY6

No regional properties for Q8CWY6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8CWY6

Functions

Description
EC Number 6.1.1.14 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glycine-tRNA ligase activity Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

1 GO annotations of biological process

Name Definition
glycyl-tRNA aminoacylation The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKLTFQEI ILTLQQYWND QGCMLMQAYD NEKGAGTMSP YTFLRAIGPE PWNAAYVEPS
70 80 90 100 110 120
RRPADGRYGE NPNRLYQHHQ FQVVMKPSPS NIQELYLQSL ELLGINALEH DIRFVEDNWE
130 140 150 160 170 180
NPSTGSAGLG WEVWLDGMEI TQFTYFQQVG GLATQPVTAE VTYGLERLAS YIQEVDSVYD
190 200 210 220 230 240
IEWAPGVKYG EIFRQPEYEH SKYSFEISNQ EMLLENFEKF EAEAKRCLEG SLVHPAYDYI
250 260 270 280 290 300
LKCSHTFNLL DARGAVSVTE RAGYIARIRN LARVAAKTFV AERRRLGYPL LDEMTREKLL
AEEEA