Q8CRT9
Gene name |
pcrA (SE_1590) |
Protein name |
ATP-dependent DNA helicase PcrA |
Names |
|
Species |
Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) |
KEGG Pathway |
sep:SE_1590 |
EC number |
5.6.2.4: Enzymes altering nucleic acid conformation |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8CRT9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8CRT9-F1 | Predicted | AlphaFoldDB |
No variants for Q8CRT9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8CRT9 | |||||
No associated diseases with Q8CRT9
Functions
| Description | ||
|---|---|---|
| EC Number | 5.6.2.4 | Enzymes altering nucleic acid conformation |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA helicase activity | Unwinding of a DNA helix, driven by ATP hydrolysis. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA unwinding involved in DNA replication | The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNALVKNMNS | EQSEAVRTTE | GPLLIMAGAG | SGKTRVLTHR | IAYLLDEKDV | SPYNILAITF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TNKAAKEMKA | RVEHLVGEEA | QVIWMSTFHS | MCVRILRRDA | DRIGIERNFT | IIDPTDQKSV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IKDVLKSENI | DSKRFEPRMF | IGAISNLKNE | LKTPEDAQKE | ANDFHSQMVA | TVYKGYQRQL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SRNEALDFDD | LIMTTINLFE | RVPETLEYYQ | NKFQYIHVDE | YQDTNKAQYT | LVKLLANKFK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NLCVVGDSDQ | SIYGWRGADI | QNILSFEEDY | PEAKTIFLEQ | NYRSTKNILN | AANEVIKHNS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ERKPKGLWTA | NSGGDKIQYY | EAMTERDEAE | YVVKEIMKHQ | RSGKKYSEMA | ILYRTNAQSR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VLEETFMKSN | IPYTMVGGQK | FYDRKEIKDL | LSYLRVIANS | NDDISLQRII | NVPKRGIGPS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SVEKIQTYAL | QNNISMFDAL | AEVDFIGLSK | KVTQECISFY | EMIQNLIKEQ | EFLEISEIVD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EVLQKSGYRD | MLDREQSIES | RSRLENLDEF | MSVPKDYEEN | TPLEEQSLIN | FLTDLSLVAD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IDEADTQNGV | TLMTMHSAKG | LEFPIVFIMG | MEESLFPHIR | AIKSEDDHEM | EEERRICYVA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ITRAEELLYI | TNATTRMLFG | RSQSNMPSRF | LKEIPEDLLD | SHTGQKRQTI | SPKSQPKRGF |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SKRTTSTKKQ | VSSSDWKVGD | KVMHKAWGEG | MVSNVNEKNG | SVELDIIFKS | EGPKRLLAQF |
| APITKKEDS |