Q8CRA8
Gene name |
hssS (SE_1942) |
Protein name |
Heme sensor protein HssS |
Names |
|
Species |
Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) |
KEGG Pathway |
sep:SE_1942 |
EC number |
2.7.13.3: Protein-histidine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8CRA8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8CRA8-F1 | Predicted | AlphaFoldDB |
No variants for Q8CRA8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8CRA8 | |||||
No associated diseases with Q8CRA8
4 regional properties for Q8CRA8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | AAA+ ATPase domain | 49 - 332 | IPR003593 |
| domain | ATPase, AAA-type, core | 53 - 100 | IPR003959-1 |
| domain | ATPase, AAA-type, core | 174 - 329 | IPR003959-2 |
| domain | Clp ATPase, C-terminal | 335 - 429 | IPR019489 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.13.3 | Protein-histidine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| phosphorelay sensor kinase activity | Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFKTLYSRIA | IYAITVILFS | ALMSFLFTNI | YYHFHLKASN | DAKIMRTLKE | AREYERTQKP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KPLDTYLKHL | GQMNYQIMTV | NEHGTKHFYG | ETFRKNTISQ | SAIKKVLNGE | DYHGIKNKPY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AFFVTGFFDN | ETDNTVGIQF | KTDDGALAVF | MRPDIGKTFS | EFRIFLAVLI | TLLLIISISL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VIASTYSIIK | PVTALKNATT | RIMKGDFSTP | IKQTRHDEIG | TLQSRFNTMR | QNLGQVDQMR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QHFVQNVSHE | IKTPLTHLQR | LLTQLELTQN | EEEKQLCINE | MFEITNQVSE | LTKELLLLSE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LDNASHLTFN | DNVHLNTLIK | DIIRHEQFRT | DEKDLVLFTE | LEDLYFRGNE | RLLHQAFNNL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IINAMKYAPQ | NSMINITLTS | TNHLIIFNIE | NDGSIAEEDA | KHIFDRFYKL | SDESSSNGLG |
| 430 | 440 | 450 | |||
| LAITQSIIHL | HHGSITLTSD | DKTQFIVKLF | I |