Q8CNE1

PR
Gene name
moeA (SE_1846)
Protein name
Molybdopterin molybdenumtransferase
Names
MPT Mo-transferase
Species
Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
KEGG Pathway
sep:SE_1846
EC number
2.10.1.1: Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

35-105 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8CNE1

Entry ID Method Resolution Chain Position Source
AF-Q8CNE1-F1 Predicted AlphaFoldDB

No variants for Q8CNE1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8CNE1

No associated diseases with Q8CNE1

3 regional properties for Q8CNE1

Type Name Position InterPro Accession
domain MoaB/Mog domain 182 - 324 IPR001453
domain MoeA, N-terminal and linker domain 9 - 173 IPR005110
domain MoeA, C-terminal, domain IV 337 - 407 IPR005111

Functions

Description
EC Number 2.10.1.1 Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
molybdopterin molybdotransferase activity Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.

2 GO annotations of biological process

Name Definition
Mo-molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVEKRTPIS VKEAIKRIMK QHVEVKNINI NLDESLGHIL AEDIVATYDI PRFNKSPYDG
70 80 90 100 110 120
FAIRSEDSQG ASGENRIEFE VIDHIGAGSV SEKTIDKNQA IRIMTGAQIP SGADAVVMFE
130 140 150 160 170 180
QTIESETTFT IRKSFKHLEN ISLQGEEIKA GDIVLHKGMR INSGVIAVLA TYGYTKVRVA
190 200 210 220 230 240
RKPTVAVIAT GSELLEVEDE LEPGKIRNSN GPMIKALAKQ FGIQVGMYKV QHDNLEKSIE
250 260 270 280 290 300
VVKKALSEHD LVITTGGVSV GDFDYLPEIY KSIQAQILFN KVAQRPGSVT TVAFADGKYL
310 320 330 340 350 360
FGLSGNPSAC YTGFELYVKP AVNKLMGAKA CYPQIIKATL MEDFNKANPF TRLIRAKATL
370 380 390 400 410
TKAGMTVIPS GFNKSGAVVA IAHANAMIML PGGTRGFKAG NIVDVILTES NSFEEELIL