Q8CJV9

PR
Gene name
clpB (SCO3661, SCH10.39c, SCH44.01c)
Protein name
Chaperone protein ClpB
Names
Species
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
KEGG Pathway
sco:SCO3661
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

109-184 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8CJV9

Entry ID Method Resolution Chain Position Source
AF-Q8CJV9-F1 Predicted AlphaFoldDB

No variants for Q8CJV9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8CJV9

No associated diseases with Q8CJV9

9 regional properties for Q8CJV9

Type Name Position InterPro Accession
domain AAA+ ATPase domain 199 - 346 IPR003593-1
domain AAA+ ATPase domain 601 - 794 IPR003593-2
domain ATPase, AAA-type, core 204 - 338 IPR003959-1
domain ATPase, AAA-type, core 600 - 761 IPR003959-2
domain Clp, repeat (R) domain 1 - 147 IPR004176
conserved_site ClpA/B, conserved site 1 296 - 308 IPR018368
domain Clp ATPase, C-terminal 768 - 857 IPR019489
conserved_site ClpA/B, conserved site 2 635 - 653 IPR028299
domain ClpA/ClpB, AAA lid domain 344 - 446 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
cellular response to heat Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDAELTNRSR DAINAASNRA VTEGNADLTP AHLLLALLQG QDNENITDLL AAVEADLAAV
70 80 90 100 110 120
RTGAERIVAG LPSVTGSTVA PPQPSREMLA VVADAQARAK ELGDEYLSTE HLLLGIAAKG
130 140 150 160 170 180
GAAGEVLEGQ GASAKKLQEA FRKARGGRRV TTADPEGQYK ALEKFGTDLT AAARDGKLDP
190 200 210 220 230 240
VIGRDQEIRR VVQVLSRRTK NNPVLIGEPG VGKTAVVEGL AQRIVKGDVP ESLKDKRLVA
250 260 270 280 290 300
LDLGAMVAGA KYRGEFEERL KTVLAEIKDS DGQVVTFIDE LHTVVGAGAG GDSAMDAGNM
310 320 330 340 350 360
LKPMLARGEL RMVGATTLDE YRERIEKDPA LERRFQQVLV AEPTVEDSIA ILRGLKGRYE
370 380 390 400 410 420
AHHKVQIADS ALVAAASLSD RYITSRFLPD KAIDLVDEAA SRLRMEIDSS PVEIDELQRS
430 440 450 460 470 480
VDRLKMEELA IGKETDAASL ERLERLRRDL ADKEEELRGL TARWEKEKQS LNRVGELKEK
490 500 510 520 530 540
LDELRGQAER AQRDGDFDTA SKLLYGEIPD LERDLEAASE AEEEVARDTM VKEEVGADDI
550 560 570 580 590 600
ADVVASWTGI PAGRLLEGET QKLLRMEDEL GKRLIGQTQA VRAVSDAVRR SRAGIADPDR
610 620 630 640 650 660
PTGSFLFLGP TGVGKTELAK ALADFLFDDE RAMVRIDMSE YSEKHSVARL VGAPPGYVGY
670 680 690 700 710 720
EEGGQLTEAV RRRPYTVVLL DEVEKAHPEV FDILLQVLDD GRLTDGQGRT VDFRNTILVL
730 740 750 760 770 780
TSNLGSQYLV DPTTGEAEKK QQVLEVVRSS FKPEFLNRLD DLVVFSALSQ EELSRIARLQ
790 800 810 820 830 840
INGLARRLAE RRLTLEVTDE ALAWLAEEGN DPAYGARPLR RLVQTAIGDR LAREILSGEI
850 860
KDGDTVRVDR FGDELIVGPA SGKTL