Q8CDV0
Gene name |
Ccdc178 |
Protein name |
Coiled-coil domain-containing protein 178 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:70950 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8CDV0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8CDV0-F1 | Predicted | AlphaFoldDB |
52 variants for Q8CDV0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs217252630 | 33 | K>E | No | EVA | |
| rs242159894 | 34 | E>A | No | EVA | |
| rs220889758 | 128 | V>A | No | EVA | |
| rs1133296061 | 130 | K>E | No | EVA | |
| rs1134611036 | 143 | K>T | No | EVA | |
| rs244883413 | 214 | L>F | No | EVA | |
| rs3408318786 | 224 | S>C | No | EVA | |
| rs255442980 | 235 | E>K | No | EVA | |
| rs238378984 | 250 | K>R | No | EVA | |
| rs31348097 | 278 | Q>K | No | EVA | |
| rs31342248 | 299 | A>T | No | EVA | |
| rs3389448753 | 305 | K>VSDG* | No | EVA | |
| rs3389490876 | 308 | V>G | No | EVA | |
| rs250557890 | 310 | K>E | No | EVA | |
| rs223176407 | 330 | Q>R | No | EVA | |
| rs262219392 | 348 | V>I | No | EVA | |
| rs31342249 | 360 | V>F | No | EVA | |
| rs31342249 | 360 | V>I | No | EVA | |
| rs224591591 | 372 | N>S | No | EVA | |
| rs3389498184 | 403 | C>* | No | EVA | |
| rs3389490879 | 407 | R>G | No | EVA | |
| rs3389469689 | 413 | Y>F | No | EVA | |
| rs256622392 | 416 | A>T | No | EVA | |
| rs47431547 | 420 | F>Y | No | EVA | |
| rs265767457 | 423 | L>* | No | EVA | |
| rs265767457 | 423 | L>S | No | EVA | |
| rs256099605 | 443 | I>T | No | EVA | |
| rs238094792 | 465 | D>N | No | EVA | |
| rs3389456917 | 493 | Y>F | No | EVA | |
| rs252328646 | 507 | V>I | No | EVA | |
| rs3389489274 | 515 | T>P | No | EVA | |
| rs216103414 | 528 | I>K | No | EVA | |
| rs243038160 | 535 | L>F | No | EVA | |
| rs31343151 | 540 | T>I | No | EVA | |
| rs256088616 | 546 | T>A | No | EVA | |
| rs245065774 | 546 | T>I | No | EVA | |
| rs238446901 | 556 | A>V | No | EVA | |
| rs226108568 | 560 | T>S | No | EVA | |
| rs258612006 | 573 | V>L | No | EVA | |
| rs245599755 | 585 | Q>* | No | EVA | |
| rs225439207 | 585 | Q>P | No | EVA | |
| rs229793652 | 608 | H>Y | No | EVA | |
| rs251003281 | 640 | T>K | No | EVA | |
| rs230295433 | 655 | I>V | No | EVA | |
| rs3389469639 | 665 | E>D | No | EVA | |
| rs244050203 | 670 | L>M | No | EVA | |
| rs243564862 | 707 | G>S | No | EVA | |
| rs3389448732 | 752 | L>M | No | EVA | |
| rs233480042 | 765 | A>T | No | EVA | |
| rs248410857 | 857 | F>L | No | EVA | |
| rs3389483637 | 861 | S>* | No | EVA | |
| rs3413126896 | 861 | S>E | No | EVA |
No associated diseases with Q8CDV0
No regional properties for Q8CDV0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8CDV0 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| ciliary basal body | A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPENEKEPAQ | PTTNEDALDT | GKTCLQIKEL | KDKERALMLA | ENARMQGLSE | FFFSRHEDKR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LYESKSTNTE | DVNKAIYFSY | PSRRHSCTLV | NIPKPCVNKM | ISHIEDVESK | IQEHLTQFEA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SFEEWTSVTK | DKEAGLDVSA | PEKQVHPEKG | KDEKCPELKK | RMETLLSEAI | HLIKSLETDR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AEAEQALKQH | KSRKKKISMK | IDSWSIWKLQ | ELPLAVQKEH | ENFSKINAEL | RSYLEDIALK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VEQLQERKEK | LEKANAKLQV | DIDYMASHSV | LLEKKRKQEL | GCLKERYHKK | FEVMEKFRAI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HEELKESVDK | CEGAKARLKN | MKVENEREIQ | EELINATSYE | KELDKLSVLD | AHYTTSIETV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NLDIEGDEEA | MNEVLRETQS | TTNELENLKK | TVDDLKRLFD | QYCWRQRKYE | NEYLEAFSNF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YSLKKTWDIE | LSNVSKDAKD | LTIVYEAQSE | ENKRIQSEIQ | SITDDIEESI | KKTAEMEEEV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| HTFVEMKMKN | NNYLKQLYKQ | AYQVGAVYHL | SRHKTEELED | KLADLKRIFK | GREELLKKLT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RGDIATGIEI | QKRLYAIEET | QFIEMQEFIR | RQVLYNMALL | EVEEQLKELE | AEAVRIRYLH |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RQHSKMLHNI | RKRKERVKKN | VDATKKKLLK | KSKKSRMELT | RTEGKRSIIH | EEIEIARGQT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VALHEKCIEL | SKEIRIMNLE | RTNYEERLKK | LQEEFFKLQF | DREHVHGVYD | HLMREKQYCE |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ERIFEEERRF | RRLIDMRKNT | LKNIRKCQDD | LLEENLRLAK | EYQSAQLIFL | KEKESYFNGY |
| 790 | 800 | 810 | 820 | 830 | 840 |
| DRLLSLNFSL | SDKKKLCQLQ | KRLDQKWQEY | FRLMILFNKT | KLAKFQGDSQ | NSIQKILAVQ |
| 850 | 860 | ||||
| EESSSLMQHI | LDFFKSFPNS | SCGEDD |