Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8CDL9

Entry ID Method Resolution Chain Position Source
AF-Q8CDL9-F1 Predicted AlphaFoldDB

62 variants for Q8CDL9

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389527492 30 P>L No EVA
rs238275620 41 D>N No EVA
rs3389509132 46 Q>H No EVA
rs3389497153 47 S>P No EVA
rs3389473527 49 P>T No EVA
rs3389532106 89 E>D No EVA
rs3389526408 184 N>H No EVA
rs3389520819 194 K>T No EVA
rs3389425461 196 R>S No EVA
rs387796059 213 P>L No EVA
rs3389473536 223 C>F No EVA
rs3389516842 233 Q>L No EVA
rs3389518526 253 K>* No EVA
rs30523370 265 L>F No EVA
rs256103268 278 S>A No EVA
rs3389526475 300 T>I No EVA
rs3407815516 308 Q>H No EVA
rs3408893789 308 Q>L No EVA
rs3407815621 309 R>W No EVA
rs3408995793 310 G>S No EVA
rs236605492 327 C>G No EVA
rs3408212343 344 E>D No EVA
rs31186942 373 S>A No EVA
rs3407894030 374 L>P No EVA
rs3389509114 380 P>L No EVA
rs3412749412 401 Q>L No EVA
rs3389526486 409 E>D No EVA
rs3389518491 433 A>V No EVA
rs3389482552 479 I>N No EVA
rs3389497155 481 E>D No EVA
rs3389497176 485 D>V No EVA
rs245881882 493 G>R No EVA
rs3389511059 503 V>D No EVA
rs3389520779 553 R>T No EVA
rs3389526448 554 T>R No EVA
rs259462192 558 K>Q No EVA
rs259842497 569 L>F No EVA
rs3389511084 589 W>S No EVA
rs250254572 626 V>A No EVA
rs217792522 643 L>Q No EVA
rs3389473510 645 D>N No EVA
rs3389527502 648 L>I No EVA
rs37099959 652 Q>P No EVA
rs226571281 674 N>S No EVA
rs3389511731 701 S>N No EVA
rs3389532130 704 A>S No EVA
rs3389517154 721 K>R No EVA
rs38489321 725 K>R No EVA
rs3389465401 726 R>M No EVA
rs225831776 728 S>L No EVA
rs3389497156 735 W>R No EVA
rs3389526464 744 N>K No EVA
rs3408893817 777 N>I No EVA
rs3408518565 779 V>A No EVA
rs3389526431 781 L>W No EVA
rs3389484015 786 E>D No EVA
rs225111217 818 Q>R No EVA
rs3389497172 819 R>Q No EVA
rs31279862 822 R>H No EVA
rs231947279 840 S>R No EVA
rs3389527555 853 T>I No EVA
rs30408461 855 H>R No EVA

No associated diseases with Q8CDL9

No regional properties for Q8CDL9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8CDL9

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

5 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
positive regulation of acrosome reaction Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
positive regulation of fertilization Any process that activates or increases the frequency, rate or extent of fertilization.
single fertilization The union of male and female gametes to form a zygote.
spermatogenesis The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9NVE4 CCDC87 Coiled-coil domain-containing protein 87 Homo sapiens (Human) PR
10 20 30 40 50 60
MEPHSQEPDL KPIYHRLLSP LSLFPSKAKP PPEPPKRPSQ DATPLQSIPL AKLKVGPLCR
70 80 90 100 110 120
QVSKRLASSG RAARVTAKDR LRLTEVILEE LKCNWREPPI EPILDYENNQ KLRQRLESYV
130 140 150 160 170 180
LISSEQLFVR YLHLLVTLPT SRRVFTESAT LSRLAVNLAR DCTVFLTSPD VYRCLLADFQ
190 200 210 220 230 240
TLLNLKHAQG GIVKLRPPPC PPGTFKLCPI PWPHSTGLDH MPCSSLNLNY LVQLSRPYDF
250 260 270 280 290 300
PSEPEPDPVE ELKSIPQLKS RQQLLWVPSM IKDKEIESRP SPMVPLPSHS PSSESHQFPT
310 320 330 340 350 360
SPVHSWLQRG QSMPCLHEGW SLADELCLLP PSPHPLTPLI LASESKPLPF RDIVAEDLKQ
370 380 390 400 410 420
KMKIMRMEWS RYSLLDSGLP PLLGVLTRRL TAQHHLEKLQ QMIKSLQEEE ASGKWDLQPP
430 440 450 460 470 480
RIIPLHPQPV TVALKVHDQV IVQVATVQLS ERYFNDSFHV EGAGVLYNHL TGELDGKAIE
490 500 510 520 530 540
EMDADRLVGN TTGEVYKELM SRVSVSHLSF EEGDQIEPSA DKDWSSYLAS SFLHQDKHMP
550 560 570 580 590 600
IINRNLVGFY SRRTSTPKPV PEKVPSLTLL PRHKSWDKRP NRHGVWMNWL KPSVSSEDYF
610 620 630 640 650 660
KYLSFQESDF LHVIFQMYEK EAPVEVPVPV QEYLDIQQPP PLLQDEELEF MQGKWDWSSV
670 680 690 700 710 720
IEDGSGPGRA YIHNLQQRLK RLWVMLEVPE QNRLDMVIKY SSNARLQQLP ALIKAWEQVL
730 740 750 760 770 780
KPIQKRESLL GRLEWFEQQA SDPNRFFQKP DLLMNRLLEE NRFRSYLQRK LNRMESNLVS
790 800 810 820 830 840
LLERIESVFG EPVTFKGRSY LKKMKQDKVE MLYWLQQQRR IRNLTQAQKT FRQSCTFTGS
850
SSQALVAPGN TPTTH