Q8CDL9
Gene name |
Ccdc87 |
Protein name |
Coiled-coil domain-containing protein 87 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:399599 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8CDL9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8CDL9-F1 | Predicted | AlphaFoldDB |
62 variants for Q8CDL9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389527492 | 30 | P>L | No | EVA | |
| rs238275620 | 41 | D>N | No | EVA | |
| rs3389509132 | 46 | Q>H | No | EVA | |
| rs3389497153 | 47 | S>P | No | EVA | |
| rs3389473527 | 49 | P>T | No | EVA | |
| rs3389532106 | 89 | E>D | No | EVA | |
| rs3389526408 | 184 | N>H | No | EVA | |
| rs3389520819 | 194 | K>T | No | EVA | |
| rs3389425461 | 196 | R>S | No | EVA | |
| rs387796059 | 213 | P>L | No | EVA | |
| rs3389473536 | 223 | C>F | No | EVA | |
| rs3389516842 | 233 | Q>L | No | EVA | |
| rs3389518526 | 253 | K>* | No | EVA | |
| rs30523370 | 265 | L>F | No | EVA | |
| rs256103268 | 278 | S>A | No | EVA | |
| rs3389526475 | 300 | T>I | No | EVA | |
| rs3407815516 | 308 | Q>H | No | EVA | |
| rs3408893789 | 308 | Q>L | No | EVA | |
| rs3407815621 | 309 | R>W | No | EVA | |
| rs3408995793 | 310 | G>S | No | EVA | |
| rs236605492 | 327 | C>G | No | EVA | |
| rs3408212343 | 344 | E>D | No | EVA | |
| rs31186942 | 373 | S>A | No | EVA | |
| rs3407894030 | 374 | L>P | No | EVA | |
| rs3389509114 | 380 | P>L | No | EVA | |
| rs3412749412 | 401 | Q>L | No | EVA | |
| rs3389526486 | 409 | E>D | No | EVA | |
| rs3389518491 | 433 | A>V | No | EVA | |
| rs3389482552 | 479 | I>N | No | EVA | |
| rs3389497155 | 481 | E>D | No | EVA | |
| rs3389497176 | 485 | D>V | No | EVA | |
| rs245881882 | 493 | G>R | No | EVA | |
| rs3389511059 | 503 | V>D | No | EVA | |
| rs3389520779 | 553 | R>T | No | EVA | |
| rs3389526448 | 554 | T>R | No | EVA | |
| rs259462192 | 558 | K>Q | No | EVA | |
| rs259842497 | 569 | L>F | No | EVA | |
| rs3389511084 | 589 | W>S | No | EVA | |
| rs250254572 | 626 | V>A | No | EVA | |
| rs217792522 | 643 | L>Q | No | EVA | |
| rs3389473510 | 645 | D>N | No | EVA | |
| rs3389527502 | 648 | L>I | No | EVA | |
| rs37099959 | 652 | Q>P | No | EVA | |
| rs226571281 | 674 | N>S | No | EVA | |
| rs3389511731 | 701 | S>N | No | EVA | |
| rs3389532130 | 704 | A>S | No | EVA | |
| rs3389517154 | 721 | K>R | No | EVA | |
| rs38489321 | 725 | K>R | No | EVA | |
| rs3389465401 | 726 | R>M | No | EVA | |
| rs225831776 | 728 | S>L | No | EVA | |
| rs3389497156 | 735 | W>R | No | EVA | |
| rs3389526464 | 744 | N>K | No | EVA | |
| rs3408893817 | 777 | N>I | No | EVA | |
| rs3408518565 | 779 | V>A | No | EVA | |
| rs3389526431 | 781 | L>W | No | EVA | |
| rs3389484015 | 786 | E>D | No | EVA | |
| rs225111217 | 818 | Q>R | No | EVA | |
| rs3389497172 | 819 | R>Q | No | EVA | |
| rs31279862 | 822 | R>H | No | EVA | |
| rs231947279 | 840 | S>R | No | EVA | |
| rs3389527555 | 853 | T>I | No | EVA | |
| rs30408461 | 855 | H>R | No | EVA |
No associated diseases with Q8CDL9
No regional properties for Q8CDL9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8CDL9 | |||
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| positive regulation of acrosome reaction | Any process that activates or increases the frequency, rate or extent of the acrosome reaction. |
| positive regulation of fertilization | Any process that activates or increases the frequency, rate or extent of fertilization. |
| single fertilization | The union of male and female gametes to form a zygote. |
| spermatogenesis | The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9NVE4 | CCDC87 | Coiled-coil domain-containing protein 87 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEPHSQEPDL | KPIYHRLLSP | LSLFPSKAKP | PPEPPKRPSQ | DATPLQSIPL | AKLKVGPLCR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QVSKRLASSG | RAARVTAKDR | LRLTEVILEE | LKCNWREPPI | EPILDYENNQ | KLRQRLESYV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LISSEQLFVR | YLHLLVTLPT | SRRVFTESAT | LSRLAVNLAR | DCTVFLTSPD | VYRCLLADFQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TLLNLKHAQG | GIVKLRPPPC | PPGTFKLCPI | PWPHSTGLDH | MPCSSLNLNY | LVQLSRPYDF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PSEPEPDPVE | ELKSIPQLKS | RQQLLWVPSM | IKDKEIESRP | SPMVPLPSHS | PSSESHQFPT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SPVHSWLQRG | QSMPCLHEGW | SLADELCLLP | PSPHPLTPLI | LASESKPLPF | RDIVAEDLKQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KMKIMRMEWS | RYSLLDSGLP | PLLGVLTRRL | TAQHHLEKLQ | QMIKSLQEEE | ASGKWDLQPP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RIIPLHPQPV | TVALKVHDQV | IVQVATVQLS | ERYFNDSFHV | EGAGVLYNHL | TGELDGKAIE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EMDADRLVGN | TTGEVYKELM | SRVSVSHLSF | EEGDQIEPSA | DKDWSSYLAS | SFLHQDKHMP |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IINRNLVGFY | SRRTSTPKPV | PEKVPSLTLL | PRHKSWDKRP | NRHGVWMNWL | KPSVSSEDYF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KYLSFQESDF | LHVIFQMYEK | EAPVEVPVPV | QEYLDIQQPP | PLLQDEELEF | MQGKWDWSSV |
| 670 | 680 | 690 | 700 | 710 | 720 |
| IEDGSGPGRA | YIHNLQQRLK | RLWVMLEVPE | QNRLDMVIKY | SSNARLQQLP | ALIKAWEQVL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| KPIQKRESLL | GRLEWFEQQA | SDPNRFFQKP | DLLMNRLLEE | NRFRSYLQRK | LNRMESNLVS |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LLERIESVFG | EPVTFKGRSY | LKKMKQDKVE | MLYWLQQQRR | IRNLTQAQKT | FRQSCTFTGS |
| 850 | |||||
| SSQALVAPGN | TPTTH |