Q8CDD8
Gene name |
Kctd20 |
Protein name |
BTB/POZ domain-containing protein KCTD20 |
Names |
Potassium channel tetramerization domain containing 20 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:66989 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
4 structures for Q8CDD8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1FO0 | X-ray | 250 A | P | 207-214 | PDB |
| 1NAN | X-ray | 230 A | M/Q | 207-214 | PDB |
| 2CLZ | X-ray | 190 A | C/M | 207-214 | PDB |
| AF-Q8CDD8-F1 | Predicted | AlphaFoldDB |
10 variants for Q8CDD8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389446378 | 37 | V>M | No | EVA | |
| rs3389362188 | 47 | P>S | No | EVA | |
| rs3389416596 | 115 | A>T | No | EVA | |
| rs3389454543 | 121 | L>F | No | EVA | |
| rs3389443717 | 157 | R>S | No | EVA | |
| rs3389447296 | 178 | V>I | No | EVA | |
| rs3389443732 | 256 | R>Q | No | EVA | |
| rs3389439184 | 268 | S>P | No | EVA | |
| rs3389447330 | 332 | K>T | No | EVA | |
| rs3389396391 | 396 | P>L | No | EVA |
No associated diseases with Q8CDD8
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of phosphorylation | Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNVHQGSDGD | WSLQPELSCL | GDEALAATQE | KEGSSLVSSG | LHSVTYPLAA | RSEDLALDYA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SQPASLPHPH | IMPLPEDNKG | SCFQSGSKRS | HEPFIVPERF | GNSGLGFGGG | AHSQAPEKVT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLVDGTRFVV | NPQIFTAHPD | TMLGRMFGPG | REYNFTRPNE | KGEYVIAEGI | SATVFRTVLD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YYKTGIINCP | DGISIPDLRD | TCDYLCINFD | FNTIRCQDLS | ALLHELSNDG | AHKQFDHYLE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ELILPIMVGC | AKKGERECHI | VVLTDEDSVD | WDEDHPPPMG | EEYSQILYSS | KLYRFFKYIE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NRDVAKTVLK | ERGLKNIRIG | IEGYPTCKEK | IKRRPGGRSE | VIYNYVQRPF | IQMSWEKEEG |
| 370 | 380 | 390 | 400 | 410 | |
| KSRHVDFQCV | RSKSLTNLVA | AGEDVLEDQE | IIMHHPPQVD | ELDRLNAPLS | QMAPNDFQD |