Q8C262

PR
Gene name
Irgc (Gm1102, Iigp5, Irgc1)
Protein name
Interferon-inducible GTPase 5
Names
Immunity-related GTPase cinema 1
Species
Mus musculus (Mouse)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

3-127 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8C262

Entry ID Method Resolution Chain Position Source
AF-Q8C262-F1 Predicted AlphaFoldDB

No variants for Q8C262

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8C262

No associated diseases with Q8C262

1 regional properties for Q8C262

Type Name Position InterPro Accession
domain IRG-type guanine nucleotide-binding (G) domain 51 - 234 IPR030385

Functions

Description
EC Number
Subcellular Localization
  • Cell projection, cilium, flagellum
  • Lipid droplet
  • Expressed in the sperm mitochondrial sheath
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

2 GO annotations of biological process

Name Definition
cellular response to interferon-beta Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATSRLPAVP EETTILMAKE ELEALRTAFE SGDIPQAASR LRELLANSET TRLEVGVTGE
70 80 90 100 110 120
SGAGKSSLIN ALRGLGAEDP GAALTGVVET TMQPSPYPHP QFPDVTLWDL PGAGSPGCSA
130 140 150 160 170 180
DKYLKQVDFG RYDFFLLVSP RRCGAVELPP SLLRSCARGR SFTLCAPRWT RIWRPPAARG
190 200 210 220 230 240
PRVSARLQLL QEIRDHCTER LRVAGVNDPR IFLVSNLSPT RYDFPMLVTT WEHDLPAHRR
250 260 270 280 290 300
HAGLLSLPDI SLEALQKKKD MLQEQVLKTA LVSGVIQALP VPGLAAAYDD ALLIRSLRGY
310 320 330 340 350 360
HRSFGLDDDS LAKLAEQVGK QAGDLRSVIR SPLANEVSPE TVLRLYSQSS DGAMRVARAF
370 380 390 400 410
ERGIPVSARW WPGVSASARS TPCSRAVSMR WLRTPNASAS KPWRKMSPRG VR