Q8BXQ8

PR
Gene name
Fam53c
Protein name
Protein FAM53C
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:66306
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

81-336 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8BXQ8

Entry ID Method Resolution Chain Position Source
AF-Q8BXQ8-F1 Predicted AlphaFoldDB

14 variants for Q8BXQ8

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389505096 6 T>A No EVA
rs3389452125 11 K>M No EVA
rs50970149 55 H>Y No EVA
rs3389493978 102 D>Y No EVA
rs3389485588 187 R>G No EVA
rs3389502483 192 P>S No EVA
rs3389493947 201 D>Y No EVA
rs3389505074 210 P>T No EVA
rs3389473374 221 S>Y No EVA
rs3412873817 260 W>R No EVA
rs3389494144 261 R>I No EVA
rs48072315 293 C>S No EVA
rs3389502437 302 F>L No EVA
rs3389489153 325 S>I No EVA

No associated diseases with Q8BXQ8

1 regional properties for Q8BXQ8

Type Name Position InterPro Accession
domain Focadhesin/RST, DUF3730 490 - 714 IPR022542

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein import into nucleus The directed movement of a protein from the cytoplasm to the nucleus.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9NYF3 FAM53C Protein FAM53C Homo sapiens (Human) PR
10 20 30 40 50 60
MITLITEQLQ KQTLDELKCT RFSVSLPLPD HADIPNCGDP FQLVSEGASW RGLPHCSCAE
70 80 90 100 110 120
FQDSLNFSYH PSGLSLHLRP PSRGNSPKEP PLSQVLSPEP PDPEKLPVPP APPSKRHCRS
130 140 150 160 170 180
LSVPVDLSRW QPVWRPAPSK LWTPIKHRGN AGGGGPQVPQ QSPPKRVSSL RFLQAPSASS
190 200 210 220 230 240
QCAPAHRPYS PPFFSLALAQ DSAQPCATSP QSGSWESDAE SLSPCPPQRR FSLSPSLGPQ
250 260 270 280 290 300
ASRFLPSARS SPASSPELPW RPRGLRNLPR SRSQPCDLDA RKTGVKRRHE EDCRRLRPSL
310 320 330 340 350 360
DFDKMNQKPY SGGLCLQETA REEGSNVSPP WFMACSPPPL SASCSPVEGS SQVLSESEEE
370 380 390
EEGSVRWERQ ALSKRTLCQQ DFGDLDLNLI EEN