AiPD: Autoinhibited Protein Database

Gene name	Cep95 (Ccdc45)
Protein name	Centrosomal protein of 95 kDa
Names	Cep95, Coiled-coil domain-containing protein 45
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:320162
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

409-489 (Predicted disordered autoinhibitory region) PR

409-489 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8BVV7-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs248792507	9	V>L	No	EVA
rs27039923	57	N>D	No	EVA
rs252407957	79	V>I	No	EVA
rs3389205865	93	D>N	No	EVA
rs3389181280	106	G>E	No	EVA
rs3389226523	137	A>D	No	EVA
rs3389226516	145	E>G	No	EVA
rs220337916	147	A>S	No	EVA
rs864259517	164	L>S	No	EVA
rs3402927544	172	E>*	No	EVA
rs3402639801	172	E>A	No	EVA
rs3389208732	172	E>D	No	EVA
rs3402080355	181	R>G	No	EVA
rs256803255	196	A>V	No	EVA
rs246067756	209	A>T	No	EVA
rs27039890	213	V>I	No	EVA
rs3402753385	229	S>*	No	EVA
rs3389173311	240	E>G	No	EVA
rs3389173341	278	I>V	No	EVA
rs262910950	297	H>Y	No	EVA
rs3389216193	327	E>D	No	EVA
rs27039888	351	L>P	No	EVA
rs224466512	357	A>T	No	EVA
rs3389186377	384	L>F	No	EVA
rs3389216108	384	L>I	No	EVA
rs27039883	393	T>M	No	EVA
rs222721286	394	G>D	No	EVA
rs3389210002	406	E>V	No	EVA
rs27039881	408	V>A	No	EVA
rs3389226512	408	V>M	No	EVA
rs27039880	431	P>L	No	EVA
rs3413157839	464	K>T	No	EVA
rs262513505	467	H>L	No	EVA
rs3389223829	471	G>R	No	EVA
rs214134334	503	G>E	No	EVA
rs3389208762	521	V>I	No	EVA
rs3389226502	532	V>I	No	EVA
rs3389222084	541	A>V	No	EVA
rs3389173353	553	S>P	No	EVA
rs27039870	558	P>L	No	EVA
rs3389214578	567	L>I	No	EVA
rs3389181230	592	M>L	No	EVA
rs27039860	602	A>V	No	EVA
rs27039856	646	R>G	No	EVA
rs3389210006	689	E>D	No	EVA
rs3389226466	733	M>I	No	EVA
rs3389212259	735	N>D	No	EVA
rs3389209949	766	L>F	No	EVA
rs3389226503	781	I>N	No	EVA
rs4229156	781	I>V	No	EVA
rs3389226507	793	D>A	No	EVA
rs3402762796	797	F>*	No	EVA
rs3389226509	800	L>Q	No	EVA
rs3389199560	812	A>V	No	EVA
rs3389181265	817	S>G	No	EVA

Type	Name	Position	InterPro Accession
domain	Domain of unknown function DUF5745	55 - 107	IPR044039

		Description
EC Number
Subcellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Cytoplasm, cytoskeleton, spindle pole
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
centrosome	A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
spindle pole	Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.

Name	Definition
No GO annotations for molecular function

Name	Definition
No GO annotations for biological process

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q96GE4	CEP95	Centrosomal protein of 95 kDa	Homo sapiens (Human)	PR