Q8BVM2
Gene name |
Antxrl |
Protein name |
Anthrax toxin receptor-like |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:239029 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8BVM2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8BVM2-F1 | Predicted | AlphaFoldDB |
42 variants for Q8BVM2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs254729075 | 80 | V>I | No | EVA | |
| rs3405054921 | 86 | S>CPPHCLI* | No | EVA | |
| rs242682004 | 131 | S>R | No | EVA | |
| rs3389317843 | 136 | K>R | No | EVA | |
| rs3389314063 | 141 | L>P | No | EVA | |
| rs3389311859 | 182 | D>G | No | EVA | |
| rs3389318629 | 182 | D>N | No | EVA | |
| rs3389330774 | 193 | T>I | No | EVA | |
| rs3389284033 | 200 | A>P | No | EVA | |
| rs3389291534 | 204 | G>R | No | EVA | |
| rs3389291529 | 237 | F>L | No | EVA | |
| rs3389317821 | 237 | F>L | No | EVA | |
| rs3389291562 | 326 | S>P | No | EVA | |
| rs3389335241 | 343 | I>N | No | EVA | |
| rs3389291567 | 363 | T>S | No | EVA | |
| rs243839120 | 370 | V>I | No | EVA | |
| rs30206478 | 410 | S>A | No | EVA | |
| rs3404514942 | 425 | A>P | No | EVA | |
| rs3389320423 | 426 | G>D | No | EVA | |
| rs3389273300 | 432 | G>S | No | EVA | |
| rs3389313737 | 438 | G>S | No | EVA | |
| rs580091936 | 441 | R>P | No | EVA | |
| rs3389317855 | 441 | R>S | No | EVA | |
| rs3389335219 | 463 | V>A | No | EVA | |
| rs3389273305 | 463 | V>I | No | EVA | |
| rs3389273327 | 465 | C>W | No | EVA | |
| rs3389313752 | 480 | C>* | No | EVA | |
| rs49850385 | 486 | P>S | No | EVA | |
| rs3705647 | 508 | A>T | No | EVA | |
| rs3389318626 | 551 | Y>H | No | EVA | |
| rs242066433 | 556 | Q>P | No | EVA | |
| rs265058775 | 567 | T>A | No | EVA | |
| rs3389317806 | 568 | N>Y | No | EVA | |
| rs3389313801 | 579 | C>S | No | EVA | |
| rs3389242747 | 586 | P>L | No | EVA | |
| rs3389284045 | 587 | N>K | No | EVA | |
| rs223422609 | 593 | F>L | No | EVA | |
| rs3405034903 | 601 | Q>L | No | EVA | |
| rs3404947727 | 603 | R>W | No | EVA | |
| rs3389320490 | 607 | S>T | No | EVA | |
| rs258231466 | 618 | H>R | No | EVA | |
| rs3389242734 | 621 | Q>L | No | EVA |
No associated diseases with Q8BVM2
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell surface | The external part of the cell wall and/or plasma membrane. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| transmembrane signaling receptor activity | Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| toxin transport | The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMSHSPSMPC | SALFLLLLLL | LPPTFKGGSL | RYHGPGWKLF | HRLSKGFRSS | HQRQTQQMRQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NVPQGQSGDD | CQGIFDLYLV | LDKSGSVADN | WIHIYSFAEG | LVKKFTNPNL | RISIITYSTE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AEVILPLTSD | SKEINKSLLV | LKNIVPQGLT | HMQKGLRKAN | EQIRKSTLGG | RIVNSVIIAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TDGLLLLKPY | LDTMEEAKKA | RRMGAIVYTV | GVFMYSKQQL | VNIAGDPDRC | FGVDEGFSAL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EGVVDPLTSK | SCTEILSVQP | TYVCAKDFYQ | VNISGHGLNN | TSNMKQVICR | FKFSDSKVVD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ESPSDMNEHS | ITCPGPKIKH | TGEDVSLQVS | LNNGISFIGN | KLIITSTNCW | SPRASQGIVF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KRTWLMFLPV | LLVTLLLLCC | TWKLCIKPKK | LPPPPPKPEK | EPEEESPPPS | SPPAPGRGPG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PGPSAGPGPG | PGPSPGSGPA | RSPVPARPPP | APLPANTNPT | VIVACCGCGN | RGMQGNLDTC |
| 490 | 500 | 510 | 520 | 530 | 540 |
| CDYFHPSCHP | MPLVWCHPKA | QGGYPGFAVM | KPSCSQASCR | QKHCLCSNRD | CFHLAEPPYP |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TRIVFQPNEK | YFSITQSHYS | PKIRFQTNQE | SLPVAQTLCS | KMCSPPNQEC | YTFKSPQSPY |
| 610 | 620 | 630 | 640 | ||
| QARYTKSPAR | MLPLLPPHTR | QSLESLCHTY | PFPPISKGPK | F |