Q8BRG8
Gene name |
Tmem209 |
Protein name |
Transmembrane protein 209 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:72649 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8BRG8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8BRG8-F1 | Predicted | AlphaFoldDB |
17 variants for Q8BRG8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388820239 | 13 | I>T | No | EVA | |
| rs3388804009 | 159 | M>K | No | EVA | |
| rs3388819178 | 162 | Y>C | No | EVA | |
| rs3412056226 | 165 | Q>* | No | EVA | |
| rs3388813679 | 176 | S>P | No | EVA | |
| rs3388804006 | 273 | W>L | No | EVA | |
| rs3388808304 | 289 | F>Y | No | EVA | |
| rs3412914100 | 318 | V>SDG* | No | EVA | |
| rs3388787520 | 325 | N>I | No | EVA | |
| rs3396665943 | 381 | K>M | No | EVA | |
| rs3396665871 | 381 | K>N | No | EVA | |
| rs3396523391 | 381 | K>Q | No | EVA | |
| rs3388814900 | 424 | S>I | No | EVA | |
| rs3388824028 | 482 | T>M | No | EVA | |
| rs3388820932 | 556 | L>* | No | EVA | |
| rs3388824029 | 558 | I>M | No | EVA | |
| rs3388813202 | 558 | I>S | No | EVA |
No associated diseases with Q8BRG8
No regional properties for Q8BRG8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8BRG8 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q96SK2 | TMEM209 | Transmembrane protein 209 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMQGDVSPNP | SLIDRTIKMR | KETETRKVVL | AWGLLNVSMA | GMIYTEMTGK | LISTYYNVTY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WPLWYIELAL | ASLFSLNALF | DFWRYFKYTV | APTSLVVSPG | QQALLGLKQA | VVQTTPPRDL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AATQISPSPP | SPSIQGQSVL | SYSPSRSPST | SPKFATSCMT | GYSPQLQGLS | SGGLGSYSPG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VTYSPVSGYN | KLASFSLSPS | SPYPTTVGPV | ESSGLRARYR | SPPTVYNSPT | DKEDYMTDLR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TLDTFLRSEE | EKQHRVKLGS | PDSTSPSTSP | TFWNYSRSVG | DYAQTLKKFQ | YQLACRSQAP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CANKDEADLI | SKQAAEEVWA | RVTMNRQLLD | HMDSWTAKFR | NWISETILVP | LVQEIESVST |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QMRRMGCPEL | QIGEASVTSL | KQAALVRAPL | IPTLNAIVQY | LDLTPNQEYL | FERIKELSQG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GCMSSFRWNR | GGDFKGRKWD | TDLPTDSAII | MHVFCTYLDS | RLPPHPKYPD | GKTFTSQHFV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QTPNKPDVTN | ENVFCIYQSA | VNPPHYELIY | QRHVYNLPKG | RNNMFHTLLM | FLYIIKTKES |
| 550 | 560 | ||||
| GMLGRVNLGL | SGVNILWIFG | E |