AiPD: Autoinhibited Protein Database

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-126 (Predicted disordered autoinhibitory region) PR

1-126 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8BM55-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs264204466	33	S>G	No	EVA
rs3395405959	152	K>R	No	EVA
rs3388754390	176	R>L	No	EVA
rs231500776	187	T>I	No	EVA
rs3388742678	200	C>S	No	EVA
rs3388746895	209	D>N	No	EVA
rs3388751633	210	K>N	No	EVA
rs3388751856	212	P>S	No	EVA
rs3388723806	224	Q>E	No	EVA
rs3388746869	227	L>M	No	EVA
rs3388740347	233	I>T	No	EVA
rs3388752103	306	P>H	No	EVA
rs246952710	376	S>N	No	EVA
rs3388754349	399	S>N	No	EVA
rs3388742735	410	H>L	No	EVA
rs236307898	427	H>Q	No	EVA
rs3388737087	432	A>V	No	EVA
rs259840709	445	V>F	No	EVA
rs3388747893	454	G>V	No	EVA
rs3388751550	456	G>R	No	EVA
rs3388737089	469	K>R	No	EVA
rs3388750989	538	Q>R	No	EVA
rs3388745091	541	N>D	No	EVA
rs3388745156	572	I>M	No	EVA
rs241988947	574	S>G	No	EVA
rs3388752070	574	S>T	No	EVA
rs3388749310	583	Y>C	No	EVA
rs227510825	592	A>T	No	EVA
rs3388750967	600	L>P	No	EVA
rs230272868	621	S>N	No	EVA
rs3388751900	630	L>Q	No	EVA
rs3388737103	639	E>D	No	EVA
rs32458115	658	L>F	No	EVA

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q8BM55

		Description
EC Number
Subcellular Localization	Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytoplasmic microtubule	Any microtubule in the cytoplasm of a cell.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.
Golgi apparatus	A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

Name	Definition
No GO annotations for molecular function

Name	Definition
apoptotic process	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q6NUQ4	TMEM214	Transmembrane protein 214	Homo sapiens (Human)	PR