Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8BGX1

Entry ID Method Resolution Chain Position Source
AF-Q8BGX1-F1 Predicted AlphaFoldDB

23 variants for Q8BGX1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs214648137 20 V>I No EVA
rs3389400885 40 D>Y No EVA
rs3389356311 57 E>K No EVA
rs3389387509 70 L>M No EVA
rs3406681957 87 H>Q No EVA
rs3406373692 88 L>M No EVA
rs3389391429 98 Y>F No EVA
rs3389383400 98 Y>N No EVA
rs3389400925 111 S>F No EVA
rs3405662389 132 G>S No EVA
rs3389382685 152 Q>L No EVA
rs3389400904 164 T>N No EVA
rs3389395831 199 Q>R No EVA
rs3389356315 211 H>Y No EVA
rs3389304230 215 V>M No EVA
rs3389391413 218 L>S No EVA
rs3389365058 241 H>L No EVA
rs3389356274 290 P>L No EVA
rs3389376217 312 L>F No EVA
rs3389365025 349 Q>R No EVA
rs32519361 351 D>N No EVA
rs3389365010 357 S>C No EVA
rs579288207 410 S>N No EVA

No associated diseases with Q8BGX1

No regional properties for Q8BGX1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8BGX1

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96HM7 PCED1B PC-esterase domain-containing protein 1B Homo sapiens (Human) PR
Q2M1K5 Pced1b PC-esterase domain-containing protein 1B Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MVRLLASEVQ QLLHNKFVVV LGDSVHRAVY KDLVLLLQKD CLLTNKQLRT KGELSFEKDQ
70 80 90 100 110 120
LKMGGELDTL HNRTDYREVR EFCSDHHLVR FYFLTRVYSE YMESVLEELQ SGNHAPDVII
130 140 150 160 170 180
MNSCLWDVSR YGRNSLSSYK QNLENLFGRM DQVLPKSCLL VWNTAMPLGD KIKAAFLPQK
190 200 210 220 230 240
CKGQYPRISV ATLKRKVTQA NLYSHAEATK HYFDVLDLNF HFRQARKHLQ GDGVHWNEHA
250 260 270 280 290 300
HRKLSYLLLA HMADAWGVEL PQRDSWEPDF EAWESSGQVE ERQPQDNLGP QVFAPSPHCP
310 320 330 340 350 360
FRPPPLLPSP GLPIRPPPLL GCPLPQPQQM PPFPLYPQVS YFSSDPVFQS DEFYIHSDSP
370 380 390 400 410 420
PPTHTGYAFE GDFSFYPQPP VPNFRPPCHQ RQAPVVHRGF PRHFARGPYS NPWRDRPRRP
430
PKHSPAGLES RPQ