Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8BGQ6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8BGQ6-F1 | Predicted | AlphaFoldDB |
33 variants for Q8BGQ6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs264177628 | 17 | H>N | No | EVA | |
| rs3388697750 | 32 | L>I | No | EVA | |
| rs3388702400 | 36 | P>A | No | EVA | |
| rs221372990 | 46 | D>E | No | EVA | |
| rs213298783 | 65 | A>V | No | EVA | |
| rs3388704814 | 71 | C>Y | No | EVA | |
| rs3388695119 | 75 | C>Y | No | EVA | |
| rs3388697779 | 82 | A>V | No | EVA | |
| rs3394708861 | 140 | E>K | No | EVA | |
| rs3394566495 | 141 | S>F | No | EVA | |
| rs3388706779 | 193 | S>R | No | EVA | |
| rs265086518 | 206 | L>R | No | EVA | |
| rs3388690448 | 207 | A>V | No | EVA | |
| rs27526992 | 211 | I>M | No | EVA | |
| rs228712082 | 223 | G>R | No | EVA | |
| rs234237839 | 228 | S>R | No | EVA | |
| rs3388704858 | 241 | P>S | No | EVA | |
| rs258594623 | 253 | S>R | No | EVA | |
| rs3388702356 | 267 | L>F | No | EVA | |
| rs3388701517 | 275 | V>L | No | EVA | |
| rs3388703545 | 276 | E>K | No | EVA | |
| rs3388701101 | 302 | I>K | No | EVA | |
| rs229898556 | 305 | H>N | No | EVA | |
| rs27526969 | 318 | V>M | No | EVA | |
| rs27526968 | 322 | T>M | No | EVA | |
| rs3388681121 | 323 | M>T | No | EVA | |
| rs222243029 | 339 | R>G | No | EVA | |
| rs3388681180 | 374 | K>E | No | EVA | |
| rs27510440 | 392 | F>I | No | EVA | |
| rs264877391 | 424 | S>N | No | EVA | |
| rs27510426 | 450 | N>D | No | EVA | |
| rs240136916 | 480 | L>V | No | EVA | |
| rs3388690443 | 484 | I>F | No | EVA |
No associated diseases with Q8BGQ6
No regional properties for Q8BGQ6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8BGQ6 | |||
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O75071 | EFCAB14 | EF-hand calcium-binding domain-containing protein 14 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKKRKELNAL | IGLAGDHRRK | KTKQGSGSHR | LLRTEPPDSD | SESSTDEEEF | GAIGNRSRFV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KGDYARCCKI | CCPLCAFVIL | AACVVASVGL | VWMQMALKED | LDVLKEKFRT | MESNQKSSFQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EIPKLNEELL | SKQKQLEKIE | SGELGLSRVW | INITEMNKQI | SLLSSAVNHL | KASVKSAADL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LSLPSTVEGL | QKSVASIGNT | LNSVHLAVEV | IQKTVDEHRT | TLGLLQGSME | NNGSNQILPS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PSPPSELDNK | SHSESAKQDI | LYLHNSLEEV | NSTVVEYQRQ | NDLKLKGMSE | TLSNLTQRLS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LIESHVVALS | KAEQRTNVSS | STMENRAATL | KRESLVTNRS | DTVQAQSMKK | EDNSNSQVSE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LREKLQLISA | LTNKPESNRP | PETTDEEQVQ | NFTSDPSALP | EFSQLLRNQI | ETQVKPLSLP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GISSIKDLQD | LFHKTGQDVD | GMLTYQELWN | SLGSAMPRPE | SLRAFDSNGD | GRYSFLELRL |
| ALGI |