Q8BG50
Gene name |
Tmem169 |
Protein name |
Transmembrane protein 169 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:271711 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8BG50
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8BG50-F1 | Predicted | AlphaFoldDB |
16 variants for Q8BG50
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs1134058112 | 50 | E>D | No | EVA | |
| rs1134650941 | 57 | S>P | No | EVA | |
| rs1131879782 | 63 | D>A | No | EVA | |
| rs3388477115 | 103 | T>I | No | EVA | |
| rs1133477904 | 145 | E>G | No | EVA | |
| rs3388477529 | 145 | E>K | No | EVA | |
| rs37187525 | 171 | V>I | No | EVA | |
| rs3388476513 | 176 | F>L | No | EVA | |
| rs3388476476 | 190 | I>N | No | EVA | |
| rs3388476614 | 203 | K>E | No | EVA | |
| rs3388477294 | 204 | I>F | No | EVA | |
| rs3388477703 | 210 | L>I | No | EVA | |
| rs47607413 | 220 | T>A | No | EVA | |
| rs3388476811 | 252 | F>C | No | EVA | |
| rs3388475596 | 265 | C>Y | No | EVA | |
| rs3388476394 | 283 | L>R | No | EVA |
No associated diseases with Q8BG50
No regional properties for Q8BG50
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8BG50 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q96HH4 | TMEM169 | Transmembrane protein 169 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEESAPVESQ | GQLPSPHHGS | LRRAVAAVLA | LDGESTLGRR | KKRRKDSRPE | SIIIYRSDNE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KTDEEPEESE | GGDRPKEEEG | EDFLDYPGDD | GVWNMPLDSR | YVTLTGTITR | GKKKGQMVDI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HVTLTEKELQ | ELTKPKELSR | EAAPEGRRAC | QVGADQGPHV | VLWTLVCLPV | VFVLSFVVSF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YYGTITWYNI | FLVYNEERTF | WHKISCCPCL | ILFYPVLIMT | MASSLGLYAA | VAQLSWSWAA |
| 250 | 260 | 270 | 280 | 290 | |
| WWRAACDMEK | GFCGWLCSKL | GLEDCSPYSI | VELLESDNIS | GNLSNKDPIQ | EVETSTV |