Q8AY29
Gene name |
ugcg-a (ugcg) |
Protein name |
Ceramide glucosyltransferase-A |
Names |
XLCGT, Glycosylceramide synthase-A, UDP-glucose ceramide glucosyltransferase-A |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:399204 |
EC number |
2.4.1.80: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8AY29
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8AY29-F1 | Predicted | AlphaFoldDB |
No variants for Q8AY29
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8AY29 | |||||
No associated diseases with Q8AY29
No regional properties for Q8AY29
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8AY29 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.80 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ceramide glucosyltransferase activity | Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine. |
| dihydroceramide glucosyltransferase activity | Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glycosphingolipid catabolic process | The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVLDLALQG | LAIFGCVLFF | VLWFMHFLSI | VYTRLHLNKK | ISDKQPYSKL | PGVSLLKPLK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GVDPNLINNL | ETFFELDYPK | FEILLCVQDL | DDPAVDVCKK | LLGKYPSDDA | KLFIGGKKVG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| INPKINNLMP | GYEVAKYDLI | WICDSGIKVK | PDTLTDMANQ | MTEKVGLVHG | LPYVADRQGF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AATLEQVYFG | TSHPRSYISA | NVTGFKCVTG | MSCLMRKEVL | DQAGGLIAFA | QYIAEDYFMA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KAIADRGWKF | SMATQVAMQN | SGCYSISQFQ | SRMIRWAKLR | INMLPATIIC | EPISECFVAS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LIIGWAAHHI | FRWDIMVFFM | CHCLAWFIFD | YIQLRGVQGG | PLNFSKLDYA | VAWFIRESMT |
| 370 | 380 | 390 | |||
| IYIFLSALWD | PTISWRTGRF | RLRCGGTAEE | ILDV |