Q8A9J0
Gene name |
uxaB |
Protein name |
Altronate oxidoreductase |
Names |
Tagaturonate dehydrogenase, Tagaturonate reductase |
Species |
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) |
KEGG Pathway |
bth:BT_0825 |
EC number |
1.1.1.58: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8A9J0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8A9J0-F1 | Predicted | AlphaFoldDB |
No variants for Q8A9J0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8A9J0 | |||||
No associated diseases with Q8A9J0
5 regional properties for Q8A9J0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Aminoacyl-tRNA synthetase, class I, conserved site | 45 - 56 | IPR001412 |
| domain | Aminoacyl-tRNA synthetase, class Ia | 17 - 560 | IPR002300 |
| domain | Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding | 605 - 752 | IPR013155 |
| domain | Valyl-tRNA synthetase, tRNA-binding arm | 811 - 876 | IPR019499 |
| domain | Valyl tRNA synthetase, anticodon-binding domain | 560 - 693 | IPR033705 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.58 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| mannitol-1-phosphate 5-dehydrogenase activity | Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+. |
| tagaturonate reductase activity | Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mannitol catabolic process | The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKALNKETAP | KVQRPERIIQ | FGEGNFLRAF | VDWIIYNMNQ | KTDFNSSVVV | VQPIDKGMVD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MLNAQDDLYH | VNLQGLDKGE | VVNSLTMIDV | ISRALNPYTQ | NDEFMKLAEQ | PEMRFVISNT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TEAGIAFDPT | CKLEDAPASS | YPGKLTQLLY | HRFKTFNGDK | TKGLIIFPCE | LIFLNGHKLK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ETIYQYIDLW | NLGNEFKTWF | EEACGVYATL | VDRIVPGFPR | KDIAAIKEKI | QYDDNLVVQA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EIFHLWVIEA | PQEVAKEFPA | DKAGLNVLFV | PSEAPYHERK | VTLLNGPHTV | LSPVAYLSGV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NIVRDACQHE | VIGKYIHKVM | FDELMETLNL | PKEELKKFAE | DVLERFNNPF | VDHAVTSIML |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NSFPKYETRD | LPGLKTYLER | KGELPKGLVL | GLAAIITYYK | GGVRADGAEI | VPNDAPEIMN |
| 430 | 440 | 450 | 460 | 470 | |
| LLKELWATGC | TKKVTEGVLA | AEFIWGEDLN | KIPGLAAAVK | ADLDSIQEKG | MLETVKGIL |