Q8A5G4

PR
Gene name
tdk
Protein name
Thymidine kinase
Names
Species
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
KEGG Pathway
bth:BT_2275
EC number
2.7.1.21: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

35-107 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8A5G4

Entry ID Method Resolution Chain Position Source
AF-Q8A5G4-F1 Predicted AlphaFoldDB

No variants for Q8A5G4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8A5G4

No associated diseases with Q8A5G4

No regional properties for Q8A5G4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8A5G4

Functions

Description
EC Number 2.7.1.21 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
thymidine kinase activity Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.
zinc ion binding Binding to a zinc ion (Zn).

3 GO annotations of biological process

Name Definition
DNA biosynthetic process The biosynthetic process resulting in the formation of DNA.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
thymidine metabolic process The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVLFSEDHIQ ETRRRGRIEV ICGSMFSGKT EELIRRMKRA KFARQRVEIF KPAIDTRYSE
70 80 90 100 110 120
EDVVSHDSHS IASTPIDSSA SILLFTSEID VVGIDEAQFF DDGLIDVCRQ LANNGIRVII
130 140 150 160 170 180
AGLDMDFKGN PFGPMPQLCA IADEVSKVHA ICVKCGDLAS FSHRTVKNDK QVLLGETAEY
190
EPLCRECYLR ARGEDGQKI