Q8A2A1

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
KEGG Pathway
bth:BT_3404
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

85-479 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8A2A1

Entry ID Method Resolution Chain Position Source
AF-Q8A2A1-F1 Predicted AlphaFoldDB

No variants for Q8A2A1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8A2A1

No associated diseases with Q8A2A1

6 regional properties for Q8A2A1

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 10 - 248 IPR003439
domain AAA+ ATPase domain 38 - 225 IPR003593
domain ABC3 transporter permease protein domain 540 - 653 IPR003838
conserved_site ABC transporter-like, conserved site 150 - 164 IPR017871
domain MacB, ATP-binding domain 10 - 226 IPR017911
domain MacB-like periplasmic core domain 284 - 500 IPR025857

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

1 GO annotations of biological process

Name Definition
translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTIRLNKVTR DLNVGIATVV EFLQKKGYTV EANPNTKISE EQYAVLVKEF STDKNLRLES
70 80 90 100 110 120
ERFIQERQNK ERNKASVSIE GFEKQQEKPK SEDVIKTVVP EDARPKFKPV GKIDLDKFSG
130 140 150 160 170 180
RRTDKVEKAP EKKVEPVVEQ PVVEQPVAEK TVVEKPVVES EVKKEEPKVE KVEVIAPKPA
190 200 210 220 230 240
PVEQPVVAPK PAVETKPVEV EKVVVEEVKK EEPKVVETAP VKAEERKVER TAEVTATVTT
250 260 270 280 290 300
PTEENASKEN EVFKIRQPEL GAKINVIGQI DLAALNQSTR PKKKSKEEKR REREEKEKVR
310 320 330 340 350 360
QDQKKLMKEA IIKEIRKEDS KQAKPGVKDN NADAARKKRN RINKEKVDVN NVATSNFAAP
370 380 390 400 410 420
RPNTQTGKGG GNHPRPQGQG QGQGNNNNNN KKNNNKDRFK KPVIKQEVSE EDVAKQVKET
430 440 450 460 470 480
LARLTTKGKN KTSKYRKEKR EMASNRMQEL EDQEMAESKV LKLTEFVTAN ELATMMDVSV
490 500 510 520 530 540
NQVIATCMSI GMMVSINQRL DAETINLVAE EFGFKTEYVS AEVAQAIVEE EDAPEDLQPR
550 560 570 580 590 600
APIVTVMGHV DHGKTSLLDY IRKANVIAGE AGGITQHIGA YNVQLEDGRR ITFLDTPGHE
610 620 630 640 650 660
AFTAMRARGA KVTDIAIIIV AADDNVMPQT KEAINHAMAA GVPIVFAINK VDKPTANPDK
670 680 690 700 710 720
IKEELAAMNY LVEEWGGKYQ SQDISAKKGM GVEDLMEKVL LEAEMLDLKA NPNRNATGSI
730 740 750 760 770 780
IESSLDKGRG YVATVLVSNG TLKVGDIVLA GTSYGRVKAM FNERNQRVKE AGPAEPALIL
790 800 810 820 830 840
GLNGAPAAGD TFHVVESDQE AREITNKREQ LAREQGLRTQ KILTLDELGR RIALGNFQEL
850 860 870 880 890 900
NIIVKGDVDG SVEALSDSLI KLSTEQIQVN VIHKGVGAIS ESDVSLAAAS DAIIVGFQVR
910 920 930 940 950 960
PSGAAAKMAE QEGVDIRKYS VIYDAIEEVK AAMEGMLAPE LKEQITATIE IREVFNITKV
970 980 990 1000 1010 1020
GLVAGAVVKT GKVKRSDKAR LIRDGIVIFT GNINALKRFK DDVKEVGTNF ECGISLVNCN
1030
DMKVGDMIET FEEIEVKQTL