Q89YY3

PR
Gene name
clpB (BT_4597)
Protein name
Chaperone protein ClpB
Names
Species
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
KEGG Pathway
bth:BT_4597
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

113-182 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q89YY3

Entry ID Method Resolution Chain Position Source
AF-Q89YY3-F1 Predicted AlphaFoldDB

No variants for Q89YY3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q89YY3

No associated diseases with Q89YY3

9 regional properties for Q89YY3

Type Name Position InterPro Accession
domain AAA+ ATPase domain 196 - 341 IPR003593-1
domain AAA+ ATPase domain 595 - 745 IPR003593-2
domain ATPase, AAA-type, core 201 - 333 IPR003959-1
domain ATPase, AAA-type, core 594 - 764 IPR003959-2
domain Clp, repeat (R) domain 3 - 144 IPR004176
conserved_site ClpA/B, conserved site 1 292 - 304 IPR018368
domain Clp ATPase, C-terminal 771 - 860 IPR019489
conserved_site ClpA/B, conserved site 2 629 - 647 IPR028299
domain ClpA/ClpB, AAA lid domain 343 - 437 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
cellular response to heat Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNFNNFTIKS QEAVQEAVNL VQSRGQQAIE PAHILHGVMK VGENVTNFIF QKLGMNGQQV
70 80 90 100 110 120
ALVVDKQIES LPKVSGGEPY LSRESNEVLQ KATQYSKEMG DEFVSLEHIL LALLTVKSTV
130 140 150 160 170 180
STILKDAGMT EKELRNAINE LRKGEKVTSQ SSEDNYQSLE KYAINLNEAA RSGKLDPVIG
190 200 210 220 230 240
RDEEIRRVLQ ILSRRTKNNP ILIGEPGTGK TAIVEGLAHR ILRGDVPENL KNKQVYSLDM
250 260 270 280 290 300
GALVAGAKYK GEFEERLKSV VNEVKKSEGD IILFIDEIHT LVGAGKGEGA MDAANILKPA
310 320 330 340 350 360
LARGELRSIG ATTLDEYQKY FEKDKALERR FQIVQVDEPD TLSTISILRG LKERYENHHH
370 380 390 400 410 420
VRIKDDAIIA AVELSSRYIT DRFLPDKAID LMDEAAAKLR MEVDSVPEEL DEISRKIKQL
430 440 450 460 470 480
EIEREAIKRE NDKPKLEIIG KELAELKEVE KSFKAKWQSE KTLMDKIQQN KVEIENLKFE
490 500 510 520 530 540
AEKAEREGDY GKVAEIRYGK LQALDKEIED TQEKLRGMQG DKAMIKEEVD AEDIADVVSR
550 560 570 580 590 600
WTGIPVSKMM QSEKDKLLHL EDELHQRVIG QDEAIEAVAD AVRRSRAGLQ DPKRPIGSFI
610 620 630 640 650 660
FLGTTGVGKT ELAKALAEFL FDDESMMTRI DMSEYQEKHS VSRLVGAPPG YVGYDEGGQL
670 680 690 700 710 720
TEAIRRKPYS VVLFDEIEKA HPDVFNILLQ VLDDGRLTDN KGRVVNFKNT IIIMTSNMGS
730 740 750 760 770 780
SYIQSQMEKL SGSNKEEVIE ETKKEVMNML KKNIRPEFLN RIDETIMFLP LTETEIRQIV
790 800 810 820 830 840
LLQIKGVQKM LAENGVELEM TDAALNFLSQ VGYDPEFGAR PVKRAIQRYL LNDLSKKLLS
850 860
QEVDRSKAII VDSNGDGLVF RN