Q89XV1

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
KEGG Pathway
bja:bll0204
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

860-944 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q89XV1

Entry ID Method Resolution Chain Position Source
AF-Q89XV1-F1 Predicted AlphaFoldDB

No variants for Q89XV1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q89XV1

No associated diseases with Q89XV1

8 regional properties for Q89XV1

Type Name Position InterPro Accession
conserved_site SEC-C motif 926 - 944 IPR004027
domain SecA DEAD-like, N-terminal 6 - 389 IPR011115
domain SecA Wing/Scaffold 657 - 867 IPR011116
domain SecA, preprotein cross-linking domain 228 - 345 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 658 IPR014018
conserved_site SecA conserved site 512 - 527 IPR020937
domain SecA, C-terminal helicase domain 407 - 628 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cell envelope Sec protein transport complex A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
ABC-type protein transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

4 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
protein transport by the Sec complex The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIGALARKFF GSANDRRVKG YQSRVNAINA LEPELIKLSD EELKARTADF KKQLAEGKTL
70 80 90 100 110 120
DDLLVPAFAT VREAAKRTLG QRHFDVQLIG GMVLHEGDIA EMKTGEGKTL VATLAVYLNA
130 140 150 160 170 180
LAGKGVHVVT VNDYLARRDS GWMGQIYGFL GMTTGVIVHG LDDAERKTAY ACDITYGTNN
190 200 210 220 230 240
EYGFDYLRDN MKYRLEDMVQ RPHFFAIVDE VDSILIDEAR TPLIISGPLD DRSDFYNTID
250 260 270 280 290 300
GFLPKLDKTD YDVDEKQRTV TLTEAGMEKI ETLLRDAGQL KGESLYDVEN VSVVHHINQA
310 320 330 340 350 360
LRAHTLFTRD KDYIVRDDEV VIIDEFTGRM MPGRRYSEGL HQALEAKEHV QVQPENQTLA
370 380 390 400 410 420
SITFQNYFRM YEKLAGMTGT AATEADELFD IYKLEVVEIP TNLSVARLDE DDEVYRTQKE
430 440 450 460 470 480
KYAAILAEIE RANARLQPVL VGTASIEKSE VLAEFLKSNG YKQIDFGKEN ALDKLYAAAR
490 500 510 520 530 540
AGKPSKLFAV LNARFHEQEA YIVAEAGVPG AITIATNMAG RGTDIKLGGS LEMRVPKETA
550 560 570 580 590 600
GIEDEAEKAR KIEQIKADVE RFREIVLKAE EIVEIEPAKG SKPAKTVTKP GGLYIIGSER
610 620 630 640 650 660
HESRRIDNQL RGRSGRQGDP GRSKFFLSLE DDLMRIFGSD RLDSMLQRLG LQEGEAIIHP
670 680 690 700 710 720
WINKALEKAQ QKVEARNFDI RKNLLKFDNV QNDQRKVIFD QRVDLMKDDS VAETVTDMRH
730 740 750 760 770 780
AFIDDLVAKH VPEHAYAEQW DVAGLKEELK RVLDLDLPVD DWAKEEGIAD EELLNRIENR
790 800 810 820 830 840
ADEHMAAKVA QWGPDVMRYV EKTILLQTLD HLWREHLIML DHLRQVIGLR GYGQRDPLQE
850 860 870 880 890 900
YKTEAFNLFQ EMSAHLREAV TAQLMRVEIV PPEQEAPVLP PMEAHKFDPN TGEDEMALAS
910 920 930 940
VTLGAPASDA AQRDPKNPAS WGKIGRNEDC PCGSGKKYKH CHGRYA