Q89KQ7
Gene name |
lpxB |
Protein name |
Lipid-A-disaccharide synthase |
Names |
|
Species |
Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) |
KEGG Pathway |
bja:bll4847 |
EC number |
2.4.1.182: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q89KQ7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q89KQ7-F1 | Predicted | AlphaFoldDB |
No variants for Q89KQ7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q89KQ7 | |||||
No associated diseases with Q89KQ7
No regional properties for Q89KQ7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q89KQ7 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.182 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipid-A-disaccharide synthase activity | Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP. |
| phospholipid binding | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMQGRDPKRK | IFLIATEESG | DRLGSALMKV | LRQRLGDGVQ | FEGVGGRTMA | REGLETLFPI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EELSIVGFAA | VVQQLPKILR | LIRETADAVL | EAVPDALVII | DSPDFTHRVA | RRVRARNPAI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PIVDYVSPQL | WAWRPGRART | MLGYVDHVLG | LLPFEPEEYR | KLGGPPCSYV | GHPLIEQLGS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LRPNAEEQKR | RNSELPVLLV | LPGSRRSEIR | HHIEVFGAAL | GRLQAEGRAF | ELMLPTMPHL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EATVREGIAS | WPVKPQIVIG | EAEKRAAFRI | AHAALAKSGT | VTLELALSGI | PMVTAYRVGA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IEAFILRRAI | RVSSVILANL | VIGEDVIPEF | LQEDCTPEKL | APALSEVLTD | SDMRRRQVEA |
| 370 | 380 | 390 | |||
| FARLDTIMST | GNKAPSVLAA | DIVLATMRKG | RR |