Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q89DG5

Entry ID Method Resolution Chain Position Source
AF-Q89DG5-F1 Predicted AlphaFoldDB

No variants for Q89DG5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q89DG5

No associated diseases with Q89DG5

2 regional properties for Q89DG5

Type Name Position InterPro Accession
conserved_site DNA methylase, N-6 adenine-specific, conserved site 224 - 230 IPR002052
domain Methyltransferase small domain 153 - 233 IPR007848

Functions

Description
EC Number 2.1.1.298 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
nucleic acid binding Binding to a nucleic acid.
protein-glutamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.
site-specific DNA-methyltransferase (adenine-specific) activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

1 GO annotations of biological process

Name Definition
peptidyl-glutamine methylation The addition of a methyl group to a glutamine residue in a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARASKKTAR GRAAPKLAKV GRGELVTLID YVRYSVSRFN EAKLAFAHGT TDPVAEAAFL
70 80 90 100 110 120
VCEALHLHPD QFEAFAHARV TAAEGKTLLD LIHQRVTTRK PAAYLVNKIY MRGLPFYVDE
130 140 150 160 170 180
RVIVPRSYIG ELLDSHFGGD GEAGSLIDHP TAVERVLDLC TGSGCLAILA AYHFPNATVD
190 200 210 220 230 240
AVDISKGALE VAARNVGEHG LDERVTLHRG DLFAPLGDNR YDLIITNPPY VDAEGMAALP
250 260 270 280 290 300
PECRAEPKLA FDGGVDGLDV VRRILRDAPE HLTPDGGLIC EIGRGRELVD EAFPELPLLW
310
LDTEDSEGEV FWIAAADLD