Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q89AF4

Entry ID Method Resolution Chain Position Source
AF-Q89AF4-F1 Predicted AlphaFoldDB

No variants for Q89AF4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q89AF4

No associated diseases with Q89AF4

8 regional properties for Q89AF4

Type Name Position InterPro Accession
domain S1 domain 135 - 200 IPR003029
domain K Homology domain 230 - 290 IPR004087-1
domain K Homology domain 301 - 374 IPR004087-2
domain Transcription termination factor NusA 4 - 342 IPR010213
repeat Transcription termination factor NusA, C-terminal duplication 440 - 489 IPR010214
domain Transcription factor NusA, N-terminal 4 - 123 IPR013735
domain RNA-binding domain, S1 133 - 200 IPR022967
domain KH domain, NusA-like 230 - 296 IPR025249

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
DNA-templated transcription termination The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.
transcription antitermination Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKEILAVVE AVSNEKSLPR EKIFEALECA LAIATKKKYD QEIDVRVKIN RKNGNFETFR
70 80 90 100 110 120
RWLVVNQVLQ PTKEITLEAA KFEDVTVKVN DYIEDKMISV TFDRITTQTA KQVIVQKVRE
130 140 150 160 170 180
AERAMIVEQF RKYFGKILTG IVKKINRESI TLDLGNNAEA LILKEDMLPR ENFRLGDRVR
190 200 210 220 230 240
GVLYAIYPES RGAQLFVTRS KPEMLIELFK IEVPEIGEEI IEIKSAARDP GSRAKIAVKS
250 260 270 280 290 300
NDKRVDAVGA CVGMRGARVQ AVSSELCGER IDIVLWDKNS AQFIINSMAP AEVSSIVLDE
310 320 330 340 350 360
DRHTIDIAVD SNNLAQAIGR NGQNVRLASQ LSGWEINVMT VDDLKLKHQE EKDKILNIFT
370 380 390 400 410 420
KYLKIDQKIS NILIDEGFSS IEELVYIPFN ELLNINSITQ ELAYSIRESA KKALCAIELE
430 440 450 460 470 480
NKKVINERKL HKDLLNLKGM NQKLAFKLAK KNIFSLEDLA EQGIDDLIDI ENLNSNTAGM
490
LIMAARNICW FGNKTSA