Q89AC6

PR
Gene name
lysA
Protein name
Diaminopimelate decarboxylase
Names
DAP decarboxylase, DAPDC
Species
Buchnera aphidicola subsp Baizongia pistaciae (strain Bp)
KEGG Pathway
bab:bbp_388
EC number
4.1.1.20: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

117-186 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q89AC6

Entry ID Method Resolution Chain Position Source
AF-Q89AC6-F1 Predicted AlphaFoldDB

No variants for Q89AC6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q89AC6

No associated diseases with Q89AC6

2 regional properties for Q89AC6

Type Name Position InterPro Accession
domain Orn/DAP/Arg decarboxylase 2, C-terminal 31 - 372 IPR022643
domain Orn/DAP/Arg decarboxylase 2, N-terminal 46 - 271 IPR022644

Functions

Description
EC Number 4.1.1.20 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
diaminopimelate decarboxylase activity Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2).
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

1 GO annotations of biological process

Name Definition
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSGLLKKKQR FSCNDILKIV SKYGTPLWVY DSNIIVKKIK ELSQFDVIRF AQKSCSNIHI
70 80 90 100 110 120
LNLFYKYNVK IDAVSLGEIE RALISKYRFT MDQDVVFTSD IIERETLNKV VQYKIPINIG
130 140 150 160 170 180
SIDMLEQVGK ISPGHNIWLR INPKFGHGHS KKTNTGGENS KHGIWDINLA FPYITKYNFK
190 200 210 220 230 240
LIGLHMHIGS GVDYCHLKRV CKAMIDQVLQ CKFKIHVISA GGGLTVPYHC NDEPVNVKNY
250 260 270 280 290 300
FFLWNKARKI ISNYLNRPIR LEIEPGRFLV AESGILVSEI RVIKKTNNRT FILVDSGFND
310 320 330 340 350 360
LIRPAMYGSY HHISVIPRDG RCVNYDDTIE AVVCGPLCES GDVFTQNEYG DIKTRILPNV
370 380 390 400 410
QIGDFLVFHD TGAYGASMSS NYNSRPLIPE ILFKDNEFHI IRRRQTMKEL LELEINCI