Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q89933
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 5E4V | X-ray | 271 A | A | 21-408 | PDB |
18 variants for Q89933
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 58 | L>S | No | |||
| 129 | Q>K | No | |||
| 137 | I>S | No | |||
| 148 | E>G | No | |||
| 262 | V>G | No | |||
| 405 | K>R | No | |||
| 434 | G>A | No | |||
| 448 | R>G | No | |||
| 465 | A>T | No | |||
| 474 | D>A | No | |||
| 478 | A>V | No | |||
| 479 | S>T | No | |||
| 483 | Q>L | No | |||
| 487 | D>G | No | |||
| 493 | D>EP | No | |||
| 516 | I>R | No | |||
| 521 | R>G | No | |||
| 522 | N>D | No |
No associated diseases with Q89933
No regional properties for Q89933
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q89933 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| helical viral capsid | The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure. |
| host cell cytoplasm | The cytoplasm of a host cell. |
| host cell viral nucleoid | The region of a host cell that contains the viral genome. |
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| viral nucleocapsid | The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| Hsp70 protein binding | Binding to a Hsp70 protein, heat shock proteins around 70kDa in size. |
| molecular adaptor activity | The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. |
| molecular condensate scaffold activity | Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural molecule activity | The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| modulation by virus of host gene expression | The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. |
| positive regulation of viral transcription | Any process that activates or increases the frequency, rate or extent of viral transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATLLRSLAL | FKRNKDKPPI | TSGSGGAIRG | IKHIIIVPIP | GDSSITTRSR | LLDRLVRLIG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NPDVSGPKLT | GALIGILSLF | VESPGQLIQR | ITDDPDVSIR | LLEVVQSDQS | QSGLTFASRG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TNMEDEADQY | FSHDDPISSD | QSRFGWFENK | EISDIEVQDP | EGFNMILGTI | LAQIWVLLAK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AVTAPDTAAD | SELRRWIKYT | QQRRVVGEFR | LERKWLDVVR | NRIAEDLSLR | RFMVALILDI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KRTPGNKPRI | AEMICDIDTY | IVEAGLASFI | LTIKFGIETM | YPALGLHEFA | GELSTLESLM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NLYQQMGETA | PYMVILENSI | QNKFSAGSYP | LLWSYAMGVG | VELENSMGGL | NFGRSYFDPA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YFRLGQEMVR | RSAGKVSSTL | ASELGITAED | ARLVSEIAMH | TTEDKISRAV | GPRQAQVSFL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| HGDQSENELP | RLGGKEDRRV | KQSRGEARES | YRETGPSRAS | DARAAHLPTG | TPLDIDTASE |
| 490 | 500 | 510 | 520 | ||
| SSQDPQDSRR | SADALLRLQA | MAGISEEQGS | DTDTPIVYND | RNLLD |