Q89703

PR
Gene name
ORF (3)
Protein name
Putative enzymatic polyprotein
Names
Species
Cassava vein mosaic virus (CsVMV)
KEGG Pathway
vg:1403416
EC number
2.7.7.49: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

111-237 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q89703

Entry ID Method Resolution Chain Position Source

No variants for Q89703

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q89703

No associated diseases with Q89703

3 regional properties for Q89703

Type Name Position InterPro Accession
domain Reverse transcriptase domain 231 - 413 IPR000477
domain Peptidase A3A, cauliflower mosaic virus-type 4 - 186 IPR000588
domain Reverse transcriptase, RNase H-like domain 511 - 600 IPR041373

Functions

Description
EC Number 2.7.7.49 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

7 GO annotations of molecular function

Name Definition
aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
metal ion binding Binding to a metal ion.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
RNA-DNA hybrid ribonuclease activity Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.

2 GO annotations of biological process

Name Definition
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKITYMTIK ISIPKYMSRI YHGLFDTGAN ICICKKKVLP DELWHKTENL VLRGFNDEKH
70 80 90 100 110 120
VAEYRADNIT IMIAKEKFII PYIYAMDEMS PDIIIGATFY NKYSPIELDI GKGIIKFTKN
130 140 150 160 170 180
NEKYPNYLVK YPKKRKLVPW TKGNPSVTET MENIGINQIE SRNPIEEEIN QILGTDIYGE
190 200 210 220 230 240
NPLEKWEKHK TLAKIELKNE TDNIYKPPML YQETDLPEFK MHIEEMIKEG FIEEKTNFED
250 260 270 280 290 300
KKYSSPAFIV NKHSEQKRGK TRMVIDYKDL NKKAKVVKYP IPNKDTLIHR SIQARYYSKF
310 320 330 340 350 360
DCKSGFYHIK LEEDSKKYTA FTVPQGYYQW KVLPFGYHNS PSIFQQFMDR IFRPYYDFII
370 380 390 400 410 420
VYIDDILVFS KTIEEHKIHI AKFRDITLAN GLIISKKKTE LCKEKIDFLG VQIEQGGIEL
430 440 450 460 470 480
QPHIINKILE KHTKIKNKTE LQSILGLLNQ IRHFIPHLAQ ILLPIQKKLK IKDEEIWTWT
490 500 510 520 530 540
KEDEEKIKLI QDYSKNLVIK MKYPINKEDM NWIIEVDASN NAYGSCLKYK PKNSKIEYLC
550 560 570 580 590 600
RYNSGTFKEN EQKYDINRKE LIAVYQGLQS YSLFTCEGNK LVRTDNSQVY YWIKNDTNKK
610 620 630 640 650
SIEFRNIKYL LAKIAVYNFE IQLIDGKTNI IADYLSRYNS SDTDGRYDEA NT