Q88XZ3

PR
Gene name
rpoB
Protein name
DNA-directed RNA polymerase subunit beta
Names
RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta
Species
Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum)
KEGG Pathway
lpl:lp_1021
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

453-527 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q88XZ3

Entry ID Method Resolution Chain Position Source
AF-Q88XZ3-F1 Predicted AlphaFoldDB

No variants for Q88XZ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q88XZ3

No associated diseases with Q88XZ3

8 regional properties for Q88XZ3

Type Name Position InterPro Accession
domain DNA-directed RNA polymerase, subunit 2, hybrid-binding domain 681 - 1066 IPR007120
conserved_site RNA polymerase, beta subunit, conserved site 919 - 931 IPR007121
domain RNA polymerase Rpb2, domain 7 1068 - 1142 IPR007641
domain RNA polymerase Rpb2, domain 2 140 - 288 IPR007642-1
domain RNA polymerase Rpb2, domain 2 381 - 415 IPR007642-2
domain RNA polymerase, beta subunit, protrusion 28 - 459 IPR007644
domain RNA polymerase Rpb2, domain 3 474 - 542 IPR007645
domain DNA-directed RNA polymerase, beta subunit, external 1 domain 552 - 619 IPR019462

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
ribonucleoside binding Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGHLVKYGK HRTRRSYARI KEVLDLPNLI EIQTDSYQWF LDEGLREMFE DIMPIDDFAG
70 80 90 100 110 120
KLSLEFVDYQ LLEPKYTVEE AREHDANYSA PLHVTLRLTN HETGEIKSQD VFFGDFPLMT
130 140 150 160 170 180
EQGTFIINGA ERVIVSQLVR SPGVYFNEEL DKNGRPSYGT TVIPNRGAWL ELETDAKNVS
190 200 210 220 230 240
YVRIDRTRKI PLTELVRALG YGSDDDIIDM LGETDSLMLT LEKDVHKNTD DSRVEESLKD
250 260 270 280 290 300
IYERLRPGEP KTADSSRSLL TARFFDPKRY DFAPVGRYKV NKKLSMKTRL MDQTLAETLA
310 320 330 340 350 360
DPDTGEVIAQ KDTVIDKNVM AKLSPYLERD DFKTVTYTPS DEAVVTNPMV LQVVKVYSQN
370 380 390 400 410 420
DPEKVVNVIG NGNIDLKFKH IVPADIIASI NYFFNLQEGL GSTDDIDHLG NRRIRSVGEL
430 440 450 460 470 480
LQNQFRIGLS RMERVVRERM SIQDAATVTP QQLINIRPVV ASIKEFFGSS QLSQFMDQTN
490 500 510 520 530 540
PLGELTHKRR LSALGPGGLT RDRAGYEVRD VHYTHYGRMC PIETPEGPNI GLINSLSSYA
550 560 570 580 590 600
KVNRSGFIET PYRRVDWTTH KVTDKIDYLA ADEEDQFVIA QANSPLNDDG SFVEDTVLAR
610 620 630 640 650 660
NKEENLETPI ENVDYMDVSP KQVVAVATAC IPFLENDDSN RALMGANMQR QAVPLLDPHA
670 680 690 700 710 720
PLIGTGIEYK AAHDSGIALI CRHEGTVEYV DAREVRVRRD DGSLDTYKLM KFRRSNGGKN
730 740 750 760 770 780
YNQRPIVKVG DHVDNDEVLA DGPAMEGGEL ALGQNPLVAF MTWNGYNFED AIIINERLVR
790 800 810 820 830 840
EDVYTSIHIE EYESEARDTK LGPEEMTREI PNVGEDALKN LDEDGIIRIG AEVKDGDILV
850 860 870 880 890 900
GKVTPKGVTE LSAEERLLHA IFGEKAREVR DTSLRVPHGG GGIIQDVKIF TRENGDELSP
910 920 930 940 950 960
GVNMMVRVYI AQKRKIQVGD KMAGRHGNKG TVSIVVPEED MPYMPDGTPI DIMLSPMGVP
970 980 990 1000 1010 1020
SRMNIGQVLE LHLGMAARKL GIHMATPVFD GAQDTDIWEA IREAGVDSDA KSIVYDGRTG
1030 1040 1050 1060 1070 1080
EPFDKRVAVG VMHYMKLSHM VDDKIHARSI GPYSLVTQQP LGGKAQFGGQ RFGEMEVWAL
1090 1100 1110 1120 1130 1140
EAYGAAYTLQ EILTYKSDDV VGRVKTYEAI VKGEPIPKPG VPESFRVLVK ELQALGLDMK
1150 1160 1170 1180 1190 1200
VLDSEDKEIE LRDMDDDDDE VVNVDALSKF KQQQDEKAAD KAAKADAAKP SETTNAQQDN
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