Q88SE8

PR
Gene name
galK
Protein name
Galactokinase
Names
Galactose kinase
Species
Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum)
KEGG Pathway
lpl:lp_3482
EC number
2.7.1.6: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

189-276 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q88SE8

Entry ID Method Resolution Chain Position Source
AF-Q88SE8-F1 Predicted AlphaFoldDB

No variants for Q88SE8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q88SE8

No associated diseases with Q88SE8

15 regional properties for Q88SE8

Type Name Position InterPro Accession
domain Immunodeficiency lentiviral matrix, N-terminal 2 - 127 IPR000071
domain Reverse transcriptase domain 631 - 821 IPR000477
domain Integrase, C-terminal, retroviral 1370 - 1417 IPR001037
domain Integrase, catalytic core 1201 - 1351 IPR001584
domain Zinc finger, CCHC-type 392 - 408 IPR001878-1
domain Zinc finger, CCHC-type 413 - 429 IPR001878-2
active_site Aspartic peptidase, active site 510 - 521 IPR001969
domain Peptidase A2A, retrovirus, catalytic 508 - 577 IPR001995
domain Ribonuclease H domain 1021 - 1144 IPR002156
domain Integrase, N-terminal zinc-binding domain 1150 - 1191 IPR003308
domain Reverse transcriptase connection 905 - 1006 IPR010659
domain Reverse transcriptase thumb 829 - 890 IPR010661
domain Retropepsins 494 - 585 IPR018061
domain Retropepsin-like catalytic domain 499 - 579 IPR034170
domain Retroviral nucleocapsid Gag protein p24, C-terminal domain 277 - 349 IPR045345

Functions

Description
EC Number 2.7.1.6 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
galactokinase activity Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+).
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
galactose metabolic process The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNTSDLKQEF TEAFDTKPER VFFSPGRINL IGEHTDYNGG HVFPCAITIG TYGVYAPRTD
70 80 90 100 110 120
TTVRMYSANI PDAGIVTFDV NDLSYDKAAG WTNYPKGMMD EIAKTGVKFD HGFDFYVHGN
130 140 150 160 170 180
MPDGAGLSSS ASIELLTGIM LNTGFNLGIS QLDLVKIGQK CENNYVGVNS GIMDQFAVGM
190 200 210 220 230 240
GKKDQAILLD TNTMDYSYAP VKLGNNVIVI MNTNKRRELA DSKYNERRSE CEEALRRLQT
250 260 270 280 290 300
KLDIKSLGDL TNDQFDEAAY LINDETLIKR ARHAVFENQR AIRATKALAD DDLTTFGELV
310 320 330 340 350 360
TASHVSLHFD YEVTGKELDT LAETAWKQPG VLGARMTGAG FGGCGIAIVD KDQVDAFKEN
370 380
VGKVYRDTIG YDADFYIAEI ADGPKEL