Q88F88

PR
Gene name
macB
Protein name
Macrolide export ATP-binding/permease protein MacB
Names
Species
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
KEGG Pathway
ppu:PP_4210
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

79-178 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q88F88

Entry ID Method Resolution Chain Position Source
AF-Q88F88-F1 Predicted AlphaFoldDB

No variants for Q88F88

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q88F88

No associated diseases with Q88F88

2 regional properties for Q88F88

Type Name Position InterPro Accession
domain Transcription regulator LuxR, C-terminal 832 - 897 IPR000792
domain MalT-like TPR region 453 - 784 IPR041617

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATPLIELCD IRKAYGGVDT PRVEVLRGIS LRVHAGEFVA IVGASGSGKS TLMNILGCLD
70 80 90 100 110 120
RPSAGSYRFA GKDVAELDSD ELAWLRREAF GFVFQGYHLI PSGSAQENVE MPAIYAGTPA
130 140 150 160 170 180
AERQARASAL LGRLGLASRT ANRPHQLSGG QQQRVSIARA LMNGGHIILA DEPTGALDSH
190 200 210 220 230 240
SGAEVMALLD ELASQGHVII LITHDREVAA RAHRVIEIRD GLVISDSAAD QPPAHAHKGI
250 260 270 280 290 300
QAEELRQRLD RGATQHGAWK GELLESLQAA WRVMWINRFR TALTLLGIII GVASVVVMLA
310 320 330 340 350 360
VGEGSKRQVM AQMAAFGSNI LYLNGSPPTL REPAGRITLD DVAAIGELPQ VKHIMPVLGE
370 380 390 400 410 420
KMMVRHGNNS QQFYVGGNNT FFPEIFNWPA VEGSFFTETD EASSAAVAVI GQKVREKMLA
430 440 450 460 470 480
PGSNPIGQYL LIGNVPFQVV GILAGKGASS GDQDSDGRIV VPFSAAAIRL FGHRDPDYIA
490 500 510 520 530 540
IAARDSGQVK DTEAAIDRLL RQRHQGKHDF ELTNDAALIQ AEARTQNSLS LMLGAIAAIS
550 560 570 580 590 600
LLVGGIGVMN IMLMTVRERT REIGIRMATG ARQRDILRQF LSEAIMLSMV GGLTGIALAL
610 620 630 640 650
VVGASLTLAD IAVAFALPAI VGAFACAVIT GVVFGFMPAR KAARLDPVKA LTSE