Q88CW6

PR
Gene name
betA
Protein name
Oxygen-dependent choline dehydrogenase
Names
CDH, CHD, Betaine aldehyde dehydrogenase, BADH
Species
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
KEGG Pathway
ppu:PP_5064
EC number
1.1.99.1: With other acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

110-291 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q88CW6

Entry ID Method Resolution Chain Position Source
AF-Q88CW6-F1 Predicted AlphaFoldDB

No variants for Q88CW6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q88CW6

No associated diseases with Q88CW6

2 regional properties for Q88CW6

Type Name Position InterPro Accession
domain Glucose-methanol-choline oxidoreductase, N-terminal 5 - 302 IPR000172
domain Glucose-methanol-choline oxidoreductase, C-terminal 395 - 529 IPR007867

Functions

Description
EC Number 1.1.99.1 With other acceptors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
betaine-aldehyde dehydrogenase activity Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.
choline dehydrogenase activity Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde.
flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.

1 GO annotations of biological process

Name Definition
glycine betaine biosynthetic process from choline The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQEFDYIIV GAGSAGNTLA TRLTEDAGVT VLLLEAGGPD YRFDFRTQMP AALAFPLQGR
70 80 90 100 110 120
RYNWAYETDP EPYMDGRRME CGRGKGLGGS SLINGMCYIR GNAMDFDGWA ELPGLEDWTY
130 140 150 160 170 180
LDCLPYFRKA ETRDIGPNDY HGGEGPVSVT TPKAGNNPLF HAMVEAGVQA GYPRTEDLNG
190 200 210 220 230 240
YQQEGFGPMD RTVTKNGRRS STARGYLDQA KKRPNLTIVT HALTDRVLFD GKRAIGVTYL
250 260 270 280 290 300
VGDSEERVEA RARKEVIVSS GAIASPQLLQ RSGVGPRALL ESLDIPVVHD LPGVGENLQD
310 320 330 340 350 360
HLELYLQYAC TQPVSLYPSL LWWNQPAIGA EWMFNGTGIG ASNQFEAGGF IRTRPEFKWP
370 380 390 400 410 420
NIQYHFLPVA INYNGSNGVK EHGFQAHMGS MRSPARGRIQ VKSKDPRQHP SILFNYMSTE
430 440 450 460 470 480
QDWQEFRDGI RLTREIMAQP ALDPYRGREI SPGADVQTDE QLDKFIREHA ETAFHPSCSC
490 500 510 520 530 540
KMGTDDMAVV DGEGRVHGMK GLRVVDASIM PLIITGNLNA TTIMIAEKIS DKIRGRKPLP
550 560
RSTAKYYVAG DAPVKGKPMR EVKQG