Q884D4

PR
Gene name
macB1
Protein name
Macrolide export ATP-binding/permease protein MacB 1
Names
Species
Pseudomonas syringae pv tomato (strain ATCC BAA-871 / DC3000)
KEGG Pathway
pst:PSPTO_2159
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

201-286 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q884D4

Entry ID Method Resolution Chain Position Source
AF-Q884D4-F1 Predicted AlphaFoldDB

No variants for Q884D4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q884D4

No associated diseases with Q884D4

6 regional properties for Q884D4

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 6 - 245 IPR003439
domain AAA+ ATPase domain 35 - 222 IPR003593
domain ABC3 transporter permease protein domain 538 - 649 IPR003838
conserved_site ABC transporter-like, conserved site 147 - 161 IPR017871
domain MacB, ATP-binding domain 6 - 223 IPR017911
domain MacB-like periplasmic core domain 283 - 500 IPR025857

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
ABC-type xenobiotic transporter activity Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

2 GO annotations of biological process

Name Definition
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
xenobiotic transport The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHTPLIDLRG IRKSYGGGDS PRVNVLRGID LSIHAGEFVA IVGASGSGKS TLMNILGCLD
70 80 90 100 110 120
RPTSGEYLFA GENVAELGGD ELAWLRREAF GFVFQGYHLI PSGSAQENVE MPAIYAGTPA
130 140 150 160 170 180
AERHARAAAL LDRLGLASRT GNRPHQLSGG QQQRVSIARA LMNGGHIILA DEPTGALDSH
190 200 210 220 230 240
SGAEVMTLLD ELASQGHVVI LITHDREVAA RANRVIEISD GLVISDTARD LSTPRSANPA
250 260 270 280 290 300
ALQAVDLRKR LSEGSGSHGA WKGELLDAIQ AAWRVMWVNR FRTALTLLGI VIGVASVVVM
310 320 330 340 350 360
LAVGEGSKRQ VMAQMSSFGS NIIYLNGKAP NPRAPKGVIT LEEVAALGEL PEVKMIMPVN
370 380 390 400 410 420
GGQAGVRFGN VDHSSYVGGN DTHFPAIFNW PVAEGSYFSE ADEQGAAAVA VIGYKVRQKL
430 440 450 460 470 480
FGDRIDPIGQ YILIENVPFQ VVGVLQEKGA TSGDLDSDNR IAIPYSSASI RLFGSQDPEY
490 500 510 520 530 540
ITIATRDANN VKQAEAAIRT LLQRLHNGKQ DYELTNNAAM IQAEARTQNT LSLMLGSIAA
550 560 570 580 590 600
ISLLVGGIGV MNIMLMTVRE RTREIGIRMA TGARQRDILR QFLTEAVMLS VVGGLAGIVL
610 620 630 640 650
ALAMGAALLA SKVAVAFTLS AVIGAFACAL VTGVIFGFMP ARKAARLDPV AALTSE