Q87R15

PR
Gene name
lpxK
Protein name
Tetraacyldisaccharide 4'-kinase
Names
Lipid A 4'-kinase
Species
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
KEGG Pathway
vpa:VP0983
EC number
2.7.1.130: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q87R15

Entry ID Method Resolution Chain Position Source
AF-Q87R15-F1 Predicted AlphaFoldDB

No variants for Q87R15

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q87R15

No associated diseases with Q87R15

No regional properties for Q87R15

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q87R15

Functions

Description
EC Number 2.7.1.130 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
tetraacyldisaccharide 4'-kinase activity Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a).

2 GO annotations of biological process

Name Definition
lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVEKIWFENH PLKYLLWPLL WPLSVLFGAI SRSKRQQFQT GRKQAYQAPV PVVVVGNITA
70 80 90 100 110 120
GGNGKTPVVV WLVEQLQHLG YKPGVVSRGY GAKAPQYPLV LNDDTPTQHC GDEPKLIHRR
130 140 150 160 170 180
TGAPVAVDPV RANAVKALVE LDVDIIITDD GLQHYALERD VELVIVDGNR RFGNECLIPL
190 200 210 220 230 240
GPLREGVERL QEVDFIITNG GLAHQGEISM SLAPSKAINL KTKQQVDVSE LKALVAFAGI
250 260 270 280 290 300
GHPPRFFNTL ESMHADVKVT KGFADHQDFD QKELEALALQ GANVIMTEKD AVKCSDYAQD
310 320 330
NWWYLPVSAQ LEPKDAERIL NRIKEVKATY GSPSA