Q876N4

PR
Gene name
ATG9 (GSA14)
Protein name
Autophagy-related protein 9
Names
Glucose-induced selective autophagy protein 14
Species
Komagataella pastoris (Yeast) (Pichia pastoris)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

19-113 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q876N4

Entry ID Method Resolution Chain Position Source
AF-Q876N4-F1 Predicted AlphaFoldDB

No variants for Q876N4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q876N4

No associated diseases with Q876N4

No regional properties for Q876N4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q876N4

Functions

Description
EC Number
Subcellular Localization
  • Preautophagosomal structure membrane ; Multi-pass membrane protein
  • Cytoplasmic vesicle membrane ; Multi-pass membrane protein
  • Vacuole membrane ; Multi-pass membrane protein
  • Golgi apparatus membrane ; Multi-pass membrane protein
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
  • The peripheral pool of ATG9 partially colocalizes with mitochondria and it has been speculated that ATG9 resides either in the mitochondria or within vesicles in very close to the mitochondria
  • During methanol growth, localizes to multiple structures situated near the plasma membrane referred as the peripheral compartment (Atg9-PC)
  • During glucose-induced micropexophagy, traffics from the Atg9-PC to unique perivacuolar structures (PVS) that contain ATG11, but lack ATG2 and ATG8
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytoplasmic vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHKNNTTFLS RVFGINSRNI DVHNPLFADD SVIPLYDQNQ SAYYDNAYSD YSSDEEDSKP
70 80 90 100 110 120
RTSRQTDSNL HMTDHSGDGN DPFNQMDNSS RFSNSSSFHY NNTDQEDDNP ELLLLQDEDS
130 140 150 160 170 180
SLNRKNLDNS DFQSFAKKTF NQIPKIKFQL PKKEDYPTSH RQPPDIENQN GTLKSSVKKQ
190 200 210 220 230 240
IHFLDPMDKA LWMWSNVSNL DTFLHQVYDY YTGNGFNCIM MNKFTELFTV VFIVWLFSFM
250 260 270 280 290 300
GNCIDYDKLM NDRNVYQFSQ VKIDKCYSKI GFFPQKLIYW LFFIGLCLKL YQIFLDYLVL
310 320 330 340 350 360
KDMKLFFNLL LGLSDDELQT ISWGLVVKRI MILRDKNINA IVSQNTDLTS RKRMNAHDIA
370 380 390 400 410 420
NRILRKENYM IAMYNKSILD LDIELPLIGK VQLLTNTLQW NLNIAILDYF FDSETGQINL
430 440 450 460 470 480
PALKERNRHT ISTELKKRLI FCGIINIVLA PILSIYFIMY YFLKFFYDFK TNPADISSRE
490 500 510 520 530 540
YSPYARWKLR EFNELPHIFN RRLNISTESS NKYINQFPKE TTTALLKFIM FISGSIVGVL
550 560 570 580 590 600
VIVTILDPEF FLNFELTPGR TVLFYVSTLG AIFTICKNSI PDDTLVFDPE VSLRYLSQFT
610 620 630 640 650 660
HYLPQEWEGK YHTEEVKNDF CKLYTLKLYL VGKEILSWLF LPYILCYKLP ECADTISDFF
670 680 690 700 710 720
REFSVHVDGL GYVCTFAMFQ FNNQHNENGN ANVHQNGNGN GGVPSAKSKS KKVPNPNRFT
730 740 750 760 770 780
TKPSMRDMEN DDKMIKSYMY FLESYGNDEI VQHQQALNRS LIYSTEISPT SGDDLNDSNI
790 800 810 820 830 840
LGLRQRNVAT TGKRQNSIGN GLIYNGQNKR LSIGEAKTNV YSNPIASTVL DKDLQYKLAN
850 860 870 880
SYILNGMPGL NEANQPADRK NERKYSNDSP GVMKLVDKIS QQHKA