Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q876K6

Entry ID Method Resolution Chain Position Source
AF-Q876K6-F1 Predicted AlphaFoldDB

No variants for Q876K6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q876K6

No associated diseases with Q876K6

2 regional properties for Q876K6

Type Name Position InterPro Accession
conserved_site Amino acid permease, conserved site 149 - 180 IPR004840
domain Amino acid permease/ SLC12A domain 124 - 589 IPR004841

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
amino acid transport The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSSTSPYEL KDLKNSSTEV HAAEQENEIE YFETDSNDRP SQQPHLDYEQ HNTSAVRRFL
70 80 90 100 110 120
DSFKRADQDQ EQEAEVAQMN DLTSAISPSS RQAHELEKDE TTDKIAPHTG HKSDSLKKTI
130 140 150 160 170 180
QPRHVLMIAL GTGIGTGLLV GNGTALVHAG PAGLLIGYAI MGSILYCIIQ ACGEMALVYS
190 200 210 220 230 240
NLTGGYNAYP SFLVDDGFGF AVAWVYCLQW LCVCPLELVT ASMTIKYWTT SVNPDVFVII
250 260 270 280 290 300
FYVLVITINI FGARGYAEAE FFFNCCKILM MTGFFILGII IDVGGAGNDG YIGGKYWHEP
310 320 330 340 350 360
GAFNGVHAID RFKGVVATLV TAAFAFGGSE FIAITTAEQS NPRKAIPGAA KQMIYRILFL
370 380 390 400 410 420
FLATIIIVGF LVPYNSDQLL GSSGGGTKAS PYVIAIASHG VRVAPHFVNA VILLSVLSMA
430 440 450 460 470 480
NSSFYSSARL FLTLSEQGYA PKIFSYIDRA GRPLIAMCVS ALFAVIAFCA ASPKEDQVFT
490 500 510 520 530 540
WLLAISGLSQ LFTWTAICLS HIRFRRAMKV QGRSLGELGF KSQTGVWGSI YSCIMMILIL
550 560 570 580 590 600
IGQFWVAIAP IGEGKLDAQA FFENYLAMPI LIVLYVGYKM WNKDWKLFIR ADKIDLTSHR
610 620 630
QIFDEELIKQ EDDEYRERLR TGPYWRRVLA FWC