Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q86D96
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q86D96-F1 | Predicted | AlphaFoldDB |
No variants for Q86D96
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q86D96 | |||||
No associated diseases with Q86D96
No regional properties for Q86D96
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q86D96 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endomembrane system | A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| G-protein beta/gamma-subunit complex binding | Binding to a complex of G-protein beta/gamma subunits. |
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| G protein-coupled receptor signaling pathway | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGCSASKPSE | PSNAKLPSAP | VPKKVEQVPE | PKPEPQPQPE | PQPQPEPPKP | AEPAPAPAPA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PEPQKPAEPA | PKVVAVEDDT | NEAYGLLLCG | AGESGKTTFT | RQLKLRYLNG | FNEKDCRDFL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RTIRGNLVET | MQLLLVWLEH | NNIEIEDSEL | SSMAQDIIDV | DPQDCEFNEE | LVEKLKALWE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NEQIKKAFEH | KDETAVPDHM | PYFFAKIDEL | AGEDYIPSNE | DVLRARIRSI | GIEAITFDLQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GARIRIFDVG | GQKSERSKWA | NVMNQVEGVI | FCVSFAEFDK | PMFEDQNVLR | INDSLEIFGN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ITHQEKFSNS | PIFLVCNKFD | VFTEKIKNTD | AFVKIFPEFS | GDSHNPEACA | DYLIQRFLDK |
| 370 | 380 | 390 | 400 | ||
| AAPLSEDRPI | IQYKIVALNG | DQVVETADAI | CKFISDKYYQ | DA |