Q86AD7

PR
Gene name
DDB_G0271550
Protein name
Probable myosin light chain kinase DDB_G0271550
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0271550
EC number
2.7.11.18: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

264-392 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

163-185 (Activation loop from InterPro)

Target domain

20-278 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q86AD7

Entry ID Method Resolution Chain Position Source
AF-Q86AD7-F1 Predicted AlphaFoldDB

No variants for Q86AD7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q86AD7

No associated diseases with Q86AD7

3 regional properties for Q86AD7

Type Name Position InterPro Accession
domain Protein kinase domain 20 - 278 IPR000719
active_site Serine/threonine-protein kinase, active site 138 - 150 IPR008271
binding_site Protein kinase, ATP binding site 26 - 49 IPR017441

Functions

Description
EC Number 2.7.11.18 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
myosin light chain kinase activity Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKLFKRIGR KKDSKIEDFY EFGPEIGRGA FSIVRQGTHK DTGDQVAIKA ISKQHVSEAD
70 80 90 100 110 120
MKRFTREIEI MKKLKHKNII QLIEVFDSND YLYLVLELIR GGELFDKIVE KGNYSEKDAC
130 140 150 160 170 180
NLVRQIVSAV EYMHQHGVCH RDLKPENLLC SGDDEKEEIV RIADFGLSKI FEGGEELKTA
190 200 210 220 230 240
CGTPDYVAPE ILECKPYDTS VDMWSIGVIT YILLCGFAPF YADTHHELFQ KILDLEYDFP
250 260 270 280 290 300
EPEWNGITDL AKDFISQLLI INPEERWTAS QCIKHPWLAE NHGDKELKSL DSAISSMKDY
310 320 330 340 350 360
VRNREASTSN ILKMRASQST PNLHSANSNT NTNSLSSSNS NNTTSNSNNN NNNNSNNSNN
370 380 390
NNNNSNNNNN INNNNNNNNN NNNNNNNNNN NI