Q869W6

PR
Gene name
DDB_G0275057
Protein name
Probable myosin light chain kinase DDB_G0275057
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0275057
EC number
2.7.11.18: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-77 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

198-220 (Activation loop from InterPro)

Target domain

56-313 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q869W6

Entry ID Method Resolution Chain Position Source
AF-Q869W6-F1 Predicted AlphaFoldDB

No variants for Q869W6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q869W6

No associated diseases with Q869W6

3 regional properties for Q869W6

Type Name Position InterPro Accession
domain Protein kinase domain 56 - 313 IPR000719
active_site Serine/threonine-protein kinase, active site 174 - 186 IPR008271
binding_site Protein kinase, ATP binding site 62 - 94 IPR017441

Functions

Description
EC Number 2.7.11.18 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
myosin light chain kinase activity Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGCFNSKEAG AGRPKTTTQQ QQQATPEPTV TTAEVRADEK ISMDQDISQG NVEDFYVVGK
70 80 90 100 110 120
ELGRGAFSVV REGTRKTTSD KVALKYIEKK FVKKKHIEQL RREIDIMKKV KHENVLSLKE
130 140 150 160 170 180
IFESDSHLTL VMELVTGGEL FYKIVERGSF TEKGARNVVR QVCAGVEYLH SQGIAHRDLK
190 200 210 220 230 240
PENLLCNGEG EDMTIKIADF GLSKIFGTGE ALETSCGTPD YVAPEVLTGG SYDNAVDMWS
250 260 270 280 290 300
IGVITYILLC GFPPFYASSQ NLLFEKILTA DYDFPEPEWT HVSEHAKAFI RNLIVKDPDQ
310 320 330 340
RHTAKQCLDD LWLSGSDQSI GSAADLHSHF AEKMKKYNDQ RRGGQSSNN