Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q84WD3

Entry ID Method Resolution Chain Position Source
AF-Q84WD3-F1 Predicted AlphaFoldDB

86 variants for Q84WD3

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06721921 4 A>P No 1000Genomes
ENSVATH06721920 4 A>V No 1000Genomes
tmp_4_10446203_T_C 11 I>V No 1000Genomes
ENSVATH06721918 13 D>G No 1000Genomes
ENSVATH12004206 16 E>D No 1000Genomes
ENSVATH06721917 16 E>K No 1000Genomes
ENSVATH14251690 26 E>D No 1000Genomes
tmp_4_10446097_C_A 46 G>V No 1000Genomes
tmp_4_10446094_G_A 47 S>F No 1000Genomes
tmp_4_10446079_C_T 52 G>E No 1000Genomes
tmp_4_10446055_G_A 60 S>L No 1000Genomes
ENSVATH14251689 62 P>S No 1000Genomes
ENSVATH06721915 67 S>I No 1000Genomes
ENSVATH02879353 68 G>S No 1000Genomes
ENSVATH00521951 71 K>R No 1000Genomes
ENSVATH00521949 73 G>R No 1000Genomes
tmp_4_10446005_C_T 77 A>T No 1000Genomes
tmp_4_10446004_G_A 77 A>V No 1000Genomes
ENSVATH02879352 79 R>H No 1000Genomes
ENSVATH06721912 81 E>G No 1000Genomes
ENSVATH12004205 85 E>K No 1000Genomes
ENSVATH00521946 89 H>Y No 1000Genomes
ENSVATH06721910 92 R>C No 1000Genomes
ENSVATH12004104 92 R>H No 1000Genomes
ENSVATH12004103 93 G>C No 1000Genomes
tmp_4_10445910_T_A 108 Q>H No 1000Genomes
ENSVATH14251687 120 V>M No 1000Genomes
ENSVATH06721909 129 T>I No 1000Genomes
tmp_4_10445822_C_T 138 E>K No 1000Genomes
ENSVATH06721908 145 F>I No 1000Genomes
ENSVATH12004102 153 Y>C No 1000Genomes
tmp_4_10445756_C_T 160 D>N No 1000Genomes
tmp_4_10445750_C_T 162 D>N No 1000Genomes
ENSVATH00521941 166 D>Y No 1000Genomes
tmp_4_10445708_C_T 176 G>R No 1000Genomes
tmp_4_10445705_C_A 177 V>F No 1000Genomes
ENSVATH02879347 191 E>D No 1000Genomes
ENSVATH12004101 194 S>I No 1000Genomes
ENSVATH06721905 195 I>N No 1000Genomes
ENSVATH02879345 197 D>G No 1000Genomes
ENSVATH06721904 199 A>V No 1000Genomes
tmp_4_10445635_C_T 200 G>E No 1000Genomes
ENSVATH02879342 210 K>N No 1000Genomes
ENSVATH06721903 212 L>F No 1000Genomes
ENSVATH00521938 222 N>H No 1000Genomes
tmp_4_10445563_A_G 224 I>T No 1000Genomes
ENSVATH02879341 225 G>E No 1000Genomes
ENSVATH06721902 229 L>V No 1000Genomes
ENSVATH02879340 230 I>V No 1000Genomes
tmp_4_10445543_C_T 231 V>M No 1000Genomes
ENSVATH12004100 241 W>C No 1000Genomes
tmp_4_10445501_G_T 245 L>I No 1000Genomes
ENSVATH02879338 252 Q>H No 1000Genomes
ENSVATH00521934 253 E>D No 1000Genomes
ENSVATH02879336 264 G>R No 1000Genomes
ENSVATH02879335 265 F>Y No 1000Genomes
ENSVATH00521933 268 K>R No 1000Genomes
ENSVATH00521932 270 I>T No 1000Genomes
tmp_4_10445406_C_G 276 E>D No 1000Genomes
ENSVATH00521931 278 L>M No 1000Genomes
ENSVATH06721900 285 E>K No 1000Genomes
ENSVATH02879334 289 L>V No 1000Genomes
ENSVATH06721899 296 S>T No 1000Genomes
ENSVATH02879331 298 A>S No 1000Genomes
ENSVATH00521929 304 I>T No 1000Genomes
ENSVATH12004099 306 I>N No 1000Genomes
ENSVATH06721897 310 P>H No 1000Genomes
ENSVATH06721897 310 P>L No 1000Genomes
ENSVATH06721895 319 T>M No 1000Genomes
tmp_4_10445271_C_G 321 L>F No 1000Genomes
ENSVATH02879327 321 L>S No 1000Genomes
ENSVATH00521924 321 L>V No 1000Genomes
ENSVATH00521923 323 D>N No 1000Genomes
ENSVATH06721894 324 A>V No 1000Genomes
ENSVATH02879325 327 T>A No 1000Genomes
tmp_4_10445254_G_A 327 T>I No 1000Genomes
ENSVATH02879323 328 N>T No 1000Genomes
ENSVATH12004031 329 A>S No 1000Genomes
ENSVATH02879322 329 A>V No 1000Genomes
ENSVATH02879321 330 G>A No 1000Genomes
tmp_4_10445246_C_T 330 G>S No 1000Genomes
ENSVATH14251686 334 A>V No 1000Genomes
ENSVATH02879319 335 P>T No 1000Genomes
ENSVATH06721890 338 N>D No 1000Genomes
ENSVATH14251685 358 L>S No 1000Genomes
ENSVATH14251654 362 M>I No 1000Genomes

No associated diseases with Q84WD3

1 regional properties for Q84WD3

Type Name Position InterPro Accession
domain NB-ARC 102 - 291 IPR002182

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ADP binding Binding to ADP, adenosine 5'-diphosphate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIAKKFISE IDDKLESKSE FDKELEKIKS SFNEEYEKWS SGKQRGSSSK HGNQSTHGDS
70 80 90 100 110 120
SPTRNSSGSS KKGRPKANRV ETSSELPDHL IRGFINEKLF LKNFLLKQKE SEEFKTLAIV
130 140 150 160 170 180
GKYGVGKTTL CQAVFNDEDV KQVYFPRIWV SMYSKETKED EDPKIDVVKR ILRSLGVEDE
190 200 210 220 230 240
MFKHIKTEAE EEKSIKDEAG EREEETVKEK ELARLLYALH LNLIGKKYLI VLDDVWEDNE
250 260 270 280 290 300
WDQRLDDEKK QQEKSHLSCG FPKGFGGKVI MTSRDERLAK AIVGEEENLQ RLFPRSDAES
310 320 330 340 350 360
LWEIYIDAVP TKVDDAAATN LGDAVATNAG DAVAPKVNPR YPGRYKQELM DKSCGIPLAA
370 380
RMLAKIEPVK VDEIGNIDRK QSF