AiPD: Autoinhibited Protein Database

Gene name	RH57 (At3g09720, F11F8_31)
Protein name	DEAD-box ATP-dependent RNA helicase 57
Names
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT3G09720
EC number	3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-161 (Predicted disordered autoinhibitory region) PR

1-161 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q84TG1-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_3_2983234_G_A	12	T>I	No	1000Genomes
tmp_3_2983194_T_A	25	K>N	No	1000Genomes
ENSVATH05799602	34	D>H	No	1000Genomes
ENSVATH05799601	41	F>L	No	1000Genomes
tmp_3_2983058_A_C	41	F>V	No	1000Genomes
tmp_3_2983048_T_C	44	E>G	No	1000Genomes
tmp_3_2983019_C_T	54	A>T	No	1000Genomes
ENSVATH00313859	58	I>V	No	1000Genomes
tmp_3_2982967_G_A	71	S>F	No	1000Genomes
ENSVATH02126298	72	V>L	No	1000Genomes
tmp_3_2982864_C_T	78	D>N	No	1000Genomes
ENSVATH02126295	84	K>R	No	1000Genomes
tmp_3_2982833_G_T	88	A>D	No	1000Genomes
ENSVATH10570213	92	A>V	No	1000Genomes
ENSVATH02126294	96	I>N	No	1000Genomes
tmp_3_2982795_T_C	101	I>V	No	1000Genomes
ENSVATH02126293	102	V>I	No	1000Genomes
ENSVATH00313858	115	R>Q	No	1000Genomes
tmp_3_2982387_C_T	147	G>S	No	1000Genomes
ENSVATH10570211	152	I>V	No	1000Genomes
ENSVATH10570208	208	T>A	No	1000Genomes
ENSVATH05799589	219	A>T	No	1000Genomes
tmp_3_2981869_G_A	240	H>Y	No	1000Genomes
tmp_3_2981845_G_A	248	L>F	No	1000Genomes
ENSVATH05799587	301	K>R	No	1000Genomes
ENSVATH10570185	334	S>A	No	1000Genomes
ENSVATH10570154	334	S>F	No	1000Genomes
ENSVATH05799586	346	R>Q	No	1000Genomes
ENSVATH02126289	358	L>V	No	1000Genomes
ENSVATH05799583	406	R>K	No	1000Genomes
tmp_3_2981105_G_A	407	A>V	No	1000Genomes
ENSVATH05799582	416	P>L	No	1000Genomes
tmp_3_2980947_T_A	425	Q>H	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Protein kinase domain	580 - 922	IPR000719
domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	580 - 909	IPR001245
conserved_site	Tyrosine-protein kinase, receptor class III, conserved site	639 - 652	IPR001824
domain	Immunoglobulin subtype 2	35 - 96	IPR003598-1
domain	Immunoglobulin subtype 2	122 - 187	IPR003598-2
domain	Immunoglobulin subtype 2	219 - 292	IPR003598-3
domain	Immunoglobulin subtype	29 - 105	IPR003599-1
domain	Immunoglobulin subtype	116 - 199	IPR003599-2
domain	Immunoglobulin subtype	213 - 303	IPR003599-3
domain	Immunoglobulin subtype	315 - 404	IPR003599-4
domain	Immunoglobulin-like domain	206 - 301	IPR007110-1
domain	Immunoglobulin-like domain	399 - 504	IPR007110-2
active_site	Tyrosine-protein kinase, active site	773 - 785	IPR008266
binding_site	Protein kinase, ATP binding site	586 - 614	IPR017441
domain	Tyrosine-protein kinase, catalytic domain	580 - 909	IPR020635

		Description
EC Number	3.6.4.13	Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
No GO annotations for cellular component

Name	Definition
ATP binding	Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity	Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding	Binding to an RNA molecule or a portion thereof.
RNA helicase activity	Unwinding of an RNA helix, driven by ATP hydrolysis.

Name	Definition
maturation of SSU-rRNA	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P45818	ROK1	ATP-dependent RNA helicase ROK1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
Q5K5B6	Os07g0647900	DEAD-box ATP-dependent RNA helicase 57	Oryza sativa subsp japonica (Rice)	PR
Q9FVV4	RH55	DEAD-box ATP-dependent RNA helicase 55	Arabidopsis thaliana (Mouse-ear cress)	PR
O22907	RH24	DEAD-box ATP-dependent RNA helicase 24	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9CAI7	TIF4A-3	Eukaryotic initiation factor 4A-3	Arabidopsis thaliana (Mouse-ear cress)	PR
O80792	RH33	Putative DEAD-box ATP-dependent RNA helicase 33	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FFQ1	RH31	DEAD-box ATP-dependent RNA helicase 31	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SA27	RH36	DEAD-box ATP-dependent RNA helicase 36	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SB89	RH27	DEAD-box ATP-dependent RNA helicase 27	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9LIH9	RH51	DEAD-box ATP-dependent RNA helicase 51	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8GY84	RH10	DEAD-box ATP-dependent RNA helicase 10	Arabidopsis thaliana (Mouse-ear cress)	PR
Q56X76	RH39	DEAD-box ATP-dependent RNA helicase 39	Arabidopsis thaliana (Mouse-ear cress)	PR
P41377	TIF4A-2	Eukaryotic initiation factor 4A-2	Arabidopsis thaliana (Mouse-ear cress)	PR
P41376	EIF4A1	Eukaryotic initiation factor 4A-1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8H0U8	RH42	DEAD-box ATP-dependent RNA helicase 42	Arabidopsis thaliana (Mouse-ear cress)	SS