Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q84JB8

Entry ID Method Resolution Chain Position Source
AF-Q84JB8-F1 Predicted AlphaFoldDB

48 variants for Q84JB8

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_4721742_G_C 9 C>S No 1000Genomes
tmp_1_4721753_A_C 13 T>P No 1000Genomes
ENSVATH04572524 24 K>N No 1000Genomes
ENSVATH11168271 36 S>F No 1000Genomes
ENSVATH11168271 36 S>Y No 1000Genomes
tmp_1_4721958_C_A 45 R>S No 1000Genomes
tmp_1_4721974_G_T 50 W>L No 1000Genomes
tmp_1_4722005_G_T 60 E>D No 1000Genomes
ENSVATH01048147 86 T>I No 1000Genomes
ENSVATH13892593 143 M>I No 1000Genomes
tmp_1_4722710_A_T 143 M>L No 1000Genomes
tmp_1_4722723_T_G 147 V>G No 1000Genomes
tmp_1_4722851_T_C 158 M>T No 1000Genomes
ENSVATH11168418 166 P>A No 1000Genomes
tmp_1_4722885_T_A 169 F>L No 1000Genomes
ENSVATH11168419 171 V>I No 1000Genomes
ENSVATH11168420 173 V>I No 1000Genomes
ENSVATH11168422 184 G>C No 1000Genomes
ENSVATH04572531 191 R>K No 1000Genomes
ENSVATH11168423 199 A>S No 1000Genomes
tmp_1_4723095_G_A 209 A>T No 1000Genomes
tmp_1_4723210_T_C 217 M>T No 1000Genomes
tmp_1_4723233_T_A 225 L>M No 1000Genomes
ENSVATH04572535 231 R>Q No 1000Genomes
tmp_1_4723305_G_A 249 V>M No 1000Genomes
ENSVATH11168516 259 V>I No 1000Genomes
ENSVATH11168517 260 R>L No 1000Genomes
tmp_1_4723644_G_A 296 G>D No 1000Genomes
ENSVATH11168518 296 G>S No 1000Genomes
ENSVATH01048152 301 W>C No 1000Genomes
ENSVATH00022256 310 S>L No 1000Genomes
ENSVATH11168519 311 K>R No 1000Genomes
tmp_1_4723714_A_T 319 L>F No 1000Genomes
tmp_1_4723728_C_T 324 S>F No 1000Genomes
tmp_1_4723835_A_T 336 N>I No 1000Genomes
tmp_1_4723837_G_A 337 G>S No 1000Genomes
tmp_1_4723995_A_C 356 N>H No 1000Genomes
ENSVATH11168522 363 K>T No 1000Genomes
tmp_1_4724025_A_G 366 K>E No 1000Genomes
tmp_1_4724070_G_A 381 A>T No 1000Genomes
ENSVATH11168523 384 M>V No 1000Genomes
tmp_1_4724095_C_T 389 S>F No 1000Genomes
ENSVATH04572542 389 S>P No 1000Genomes
tmp_1_4724100_T_G 391 Y>D No 1000Genomes
ENSVATH01048154 401 H>Y No 1000Genomes
ENSVATH13892637 402 Y>D No 1000Genomes
tmp_1_4724138_C_G 403 D>E No 1000Genomes
ENSVATH04572545 422 P>S No 1000Genomes

No associated diseases with Q84JB8

No regional properties for Q84JB8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q84JB8

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96GQ5 RUSF1 RUS family member 1 Homo sapiens (Human) PR
Q91W34 Rusf1 RUS family member 1 Mus musculus (Mouse) PR
B6IDH3 RUS5 Protein root UVB sensitive 5 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MREEQVSDCG SITLEEWNGS SSTKLFKTAT ITASSSLSIQ RSANRFNHVW RRVLQAFVPE
70 80 90 100 110 120
GFPGSVTPDY VGFQLWDTLQ GLSTYTKMML STQALLSAIG VGEKSATVIG ATFQWFLRDF
130 140 150 160 170 180
TGMLGGILFT FYQGSNLDSN AKMWRLVADL MNDIGMLMDL LSPLFPSAFI VVVCLGSLSR
190 200 210 220 230 240
SFTGVASGAT RAALTQHFAL QDNAADISAK EGSQETMATM MGMSLGMLLA RFTSGNPMAI
250 260 270 280 290 300
WLSFLSLTVF HMYANYRAVR CLVLNSLNFE RSSILLTHFI QTGQVLSPEQ VSSMEGVLPL
310 320 330 340 350 360
WATSLRSTNS KPLHKRVQLG VRVSSLPRLD MLQLLNGVGA SSYKNAKYLL AHIKGNVSVI
370 380 390 400 410 420
LHKDSKPADV LKSYIHAIVL ANLMEKSTSF YSEGEAWIDK HYDELLHKLR SGGWKTERLL
430
SPSITWRANW ISHTSAAKFD