Q83SQ0

PR
Gene name
lptD
Protein name
LPS-assembly protein LptD
Names
Species
Shigella flexneri
KEGG Pathway
sfx:S0053
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

3-81 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q83SQ0

Entry ID Method Resolution Chain Position Source
4Q35 X-ray 239 A A 1-784 PDB
AF-Q83SQ0-F1 Predicted AlphaFoldDB

No variants for Q83SQ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q83SQ0

No associated diseases with Q83SQ0

2 regional properties for Q83SQ0

Type Name Position InterPro Accession
domain Organic solvent tolerance-like, N-terminal 53 - 194 IPR005653
domain LptD, C-terminal 309 - 697 IPR007543

Functions

Description
EC Number
Subcellular Localization
  • Cell outer membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cell outer membrane A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
Gram-negative-bacterium-type cell outer membrane assembly The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.
lipopolysaccharide transport The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
response to organic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKRIPTLLA TMIATALYSQ QGLAADLASQ CMLGVPSYDR PLVQGDTNDL PVTINADHAK
70 80 90 100 110 120
GDYPDDAVFT GSVDIMQGNS RLQADEVQLH QKEAPGQPEP VRTVDALGNV HYDDNQVILK
130 140 150 160 170 180
GPKGWANLNT KDTNVWEGDY QMVGRQGRGK ADLMKQRGEN RYTILDNGSF TSCLPGSDTW
190 200 210 220 230 240
SVVGSEIIHD REEQVAEIWN ARFKVGPVPI FYSPYLQLPV GDKRRSGFLI PNAKYTTTNY
250 260 270 280 290 300
FEFYLPYYWN IAPNMDATIT PHYMHRRGNI MWENEFRYLS QAGAGLMELD YLPSDKVYED
310 320 330 340 350 360
EHPNDDSSRR WLFYWNHSGV MDQVWRFNVD YTKVSDPSYF NDFDNKYGSS TDGYATQKFS
370 380 390 400 410 420
VGYAVQNFNA TVSTKQFQVF SEQNTSSYSA EPQLDVNYYQ NDVGPFDTRI YGQAVHFVNT
430 440 450 460 470 480
RDDMPEATRV HLEPTINLPL SNNWGSINTE AKFLATHYQQ TNLDWYNSRN TTKLDESVNR
490 500 510 520 530 540
VMPQFKVDGK MVFERDMEML APGYTQTLEP RAQYLYVPYR DQSDIYNYDS SLLQSDYSGL
550 560 570 580 590 600
FRDRTYGGLD RIASANQVTT GVTSRIYDDA AVERFNISVG QIYYFTESRT GDDNITWEND
610 620 630 640 650 660
DKTGSLVWAG DTYWRISERW GLRGGIQYDT RLDNVATSNS SIEYRRDEDR LVQLNYHYAS
670 680 690 700 710 720
PEYIQATLPK YYSTAEQYKN GISQVGAVAS RPIADRWSIV GAYYYDTNAN KQADSMLGVQ
730 740 750 760 770 780
YSSCCYAIRV GYERKLNGWD NDKQHAVYDN AIGFNIELRG LSSNYGLGTQ EMLRSNILPY
QNTL